"CDH1" Related Products

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Recombinant Human CDH1 protein, Fc-tagged

Cat.No.: CDH1-275H
Product Overview: Recombinant Human CDH1(Gln 23 - Pro 621) fused with a human IgG1 Fc tag at the C-terminus was expressed in HEK293.
Source: HEK293
Species: Human
Tag: Fc
Predicted N Terminal: Gln 23
Form: Lyophilized from 0.22 μm filtered solution in 50 mM tris, 100 mM glycine, pH7.5. Normally Mannitol or Trehalose are added as protectants before lyophilization.
Molecular Mass: Has a calculated MW of 92.4 kDa. As a result of different glycosylation, DTT-reduced Protein migrates as 110-125 kDa Cadherin, a 48kDa Propeptide and non-reduced protein migrates as 200-250 kDa in SDS-PAGE .
Protein length: Gln 23 - Pro 621
Endotoxin: Less than 1.0 EU per μg of the Human E-Cadherin, Fc Tag by the LAL method.
Purity: >95% as determined by SDS-PAGE.
Storage: Avoid repeated freeze-thaw cycles.No activity loss was observed after storage at:In lyophilized state for 1 year (4 centigrade); After reconstitution under sterile conditions for 3 months (-70 centigrade).
Gene Name: CDH1 cadherin 1, type 1, E-cadherin (epithelial) [ Homo sapiens ]
Official Symbol: CDH1
Synonyms: CDH1; cadherin 1, type 1, E-cadherin (epithelial); UVO; cadherin-1; CD324; E Cadherin; uvomorulin; CAM 120/80; E-Cadherin; cell-CAM 120/80; epithelial cadherin; cadherin 1, E-cadherin (epithelial); calcium-dependent adhesion protein, epithelial; CDHE; ECAD; LCAM; Arc-1;
Gene ID: 999
mRNA Refseq: NM_004360
Protein Refseq: NP_004351
MIM: 192090
UniProt ID: P12830
Chromosome Location: 16q22.1
Pathway: Adaptive Immune System, organism-specific biosystem; Adherens junction, organism-specific biosystem; Adherens junction, conserved biosystem; Adherens junctions interactions, organism-specific biosystem; Apoptosis, organism-specific biosystem; Apoptotic cleavage of cell adhesionproteins, organism-specific biosystem; Apoptotic cleavage of cellular proteins, organism-specific biosystem;
Function: GTPase activating protein binding; calcium ion binding; cell adhesion molecule binding; gamma-catenin binding; protein binding;

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Optional requirements on this protein    +Expand
C-fusion    N-fusion   Non-tagged
His    GST   Fc   Others
<1.0 eu/μg    <0.1 eu/μg   <0.01 eu/μg   Not required
Monomer Isolation    Dimer Isolation    Not required
>80% by SDS-PAGE    >90% by SDS-PAGE   >95% by SDS-PAGE   Others

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