| Description : |
This gene encodes a type II classical cadherin from the cadherin superfamily, integral membrane proteins that mediate calcium-dependent cell-cell adhesion. Mature cadherin proteins are composed of a large N-terminal extracellular domain, a single membrane-spanning domain, and a small, highly conserved C-terminal cytoplasmic domain. Type II (atypical) cadherins are defined based on their lack of a HAV cell adhesion recognition sequence specific to type I cadherins. Expression of this particular cadherin in osteoblastic cell lines, and its upregulation during differentiation, suggests a specific function in bone development and maintenance. |
| Source : |
HEK293 |
| Species : |
Human |
| Tag : |
Myc/DDK |
| Molecular Mass : |
88 kDa |
| AA Sequence : |
MKENYCLQAALVCLGMLCHSHAFAP ERRGHLRPSFHGHHEKGKEGQVLQR SKRGWVWNQFFVIEEYTGPDPVLVG RLHSDIDSGDGNIKYILSGEGAGTI FVIDDKSGNIHATKTLDREERAQYT LMAQAVDRDTNRPLEPPSEFIVKVQ DINDNPPEFLHETYHANVPERSNVG TSVIQVTASDADDPTYGNSAKLVYS ILEGQPYFSVEAQTGIIRTALPNMD REAKEEYHVVIQAKDMGGHMGGLSG TTKVMITLTDVNDNPPKFPQSVYQM SVSEAAVPGEEVGRVKAKDPDIGEN GLVTYNIVDGDGMESFEITTDYETQ EGVIKLKKPVDFETKRAYSLKVEAA NVHIDPKFISNGPFKDTVTVKIAVE DADEPPMFLAPSYIHEVQENAAAGT VVGRVHAKDPDAANSPIRYSIDRHT DLDRFFTINPEDGFIKTTKPLDREE TAWLNITVFAAEIHNRHQEAKVPVA IRVLDVNDNAPKFAAPYEGFICESD QTKPLSNQPIVTISADDKDDTANGP RFIFSLPPEIIHNPNFTVRDNRDNT AGVYARRGGFSRQKQDLYLLPIVIS DGGIPPMSSTNTLTIKVCGCDVNGA LLSCNAEAYILNAGLSTGALIAILA CIVILLVIVVLFVTLRRQKKEPLIV FEEEDVRENIITYDDEGGGEEDTEA FDIATLQNPDGINGFIPRKDIKPEY QYMPRPGLRPAPNSVDVDDFINTRI QEADNDPTAPPYDSIQIYGYEGRGS VAGSLSSLESATTDSDLDYDYLQNW GPRFKKLADLYGSKDTFDDDSTRTR PLEQKLISEEDLAANDILDYKDDDD KV |
| Purity : |
> 80% as determined by SDS-PAGE and Coomassie blue staining |
| Stability : |
Stable for 3 months from receipt of products under proper storage and handling conditions. |
| Storage : |
Store at -80 centigrade. Avoid repeated freeze-thaw cycles. |
| Concentration : |
50 μg/mL as determined by BCA |
| Storage Buffer : |
100 mM glycine, 25 mM Tris-HCl, pH 7.3. |
