Recombinant Human CDH7 Protein, GST-Tagged

• Cat.No.: CDH7-0994H
• Product Overview: Human CDH7 full-length ORF (AAH36786, 1 a.a. - 630 a.a.) recombinant protein with GST-tag at N-terminal.

Specification

• Description: This gene encodes a type II classical cadherin of the cadherin superfamily. Alternative splicing results in multiple transcript variants, at least one of which encodes a preproprotein that is proteolytically processed to generate the mature glycoprotein. This calcium dependent cell-cell adhesion molecule is comprised of five extracellular cadherin repeats, a transmembrane region and a highly conserved cytoplasmic tail. Type II (atypical) cadherins are defined based on their lack of a histidine-alanine-valine (HAV) cell adhesion recognition sequence specific to type I cadherins. Cadherins mediate cell-cell binding in a homophilic manner, contributing to the sorting of heterogeneous cell types. Mutations in this gene may be associated with bipolar disease in human patients. This gene is present in a gene cluster on chromosome 18. [provided by RefSeq, May 2016]
• Source: Wheat Germ
• Species: Human
• Tag: GST
• Molecular Mass: 95.04 kDa
• AA Sequence: MKLGKVEFCHFLQLIALFLCFSGMS QAELSRSRSKPYFQSGRSRTKRSWV WNQFFVLEEYMGSDPLYVGKLHSDV DKGDGSIKYILSGEGASSIFIIDEN TGDIHATKRLDREEQAYYTLRAQAL DRLTNEPVEPESEFVIKIQDINDNE PKFLDGPYTAGVPEMSPVGTSVVQV TATDADDPTYGNSARVVYSILQGQP YFSVEPKTGVIKTALPNMDREAKDQ YLLVIQAKDMVGQNGGLSGTTSVTV TLTDVNDNPPRFPRRSYQYNVPESL PVASVVARIKAADADIGANAEMEYK IVDGDGLGIFKISVDKETQEGIITI QKELDFEAKTSYTLRIEAANKDADP RFLSLGPFSDTTTVKIIVEDVDEPP VFSSPLYPMEVSEATQVGNIIGTVA AHDPDSSNSPVRYSIDRNTDLERYF NIDANSGVITTAKSLDRETNAIHNI TVLAMESQNPSQVGRGYVAITILDI NDNAPEFAMDYETTVCENAQPGQVI QKISAVDKDEPSNGHQFYFSLTTDA TNNHNFSLKDNKDNTASILTRRNGF RRQEQSVYYLPIFIVDSGSPSLSST STLTIRVCDCDADGVAQTCNAEAYV LPAGLSTGALIAILACVLTLLGRYC FQGLL
• Applications: Enzyme-linked Immunoabsorbent Assay
  Western Blot (Recombinant protein)
  Antibody Production
  Protein Array
• Storage: Store at -80 centigrade. Aliquot to avoid repeated freezing and thawing.
• Storage Buffer: 50 mM Tris-HCI, 10 mM reduced Glutathione, pH=8.0 in the elution buffer.

Gene Information

• Gene Name: CDH7 cadherin 7, type 2 [ Homo sapiens ]
• Official Symbol: CDH7
• Synonyms: CDH7; cadherin 7, type 2; cadherin-7; CDH7L1
• Gene ID: 1005
• mRNA Refseq: NM_004361
• Protein Refseq: NP_004352
• MIM: 605806
• UniProt ID: Q9ULB5