Recombinant Human CDK1 & CCNE1 protein, His&GST-tagged

• Cat.No.: CDK1 & CCNE1-2209H
• Product Overview: Recombinant Human CDK1 & CCNE1 protein(NP_001777.1 & NP_001229.1)(Met1-Met297 & Met1-Ala410), fused with His&GST tag, was expressed in Insect Cells.

Specification

• Source: Insect Cells
• Species: Human
• Tag: His&GST
• Form: Lyophilized from sterile 20 mM Tris, 500 mM NaCl, 2 mM GSH, 10 % glycerol, pH 8.0.
• Molecular Mass: The recombinant heterotrimer of human CDC2 & CCNE1 comprises 950 (522+428) amino acids and has a calculated molecular mass of 109.7 (60.4+49.3) kDa.
• Protein Length: Met1-Met297 & Met1-Ala410
• Endotoxin: < 1.0 EU per μg protein as determined by the LAL method.
• Purity: > 90 % as determined by SDS-PAGE
• Storage: Samples are stable for up to twelve months from date of receipt at -20°C to -80°C
  Store it under sterile conditions at -20°C to -80°C. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
• Reconstitution: It is recommended that sterile water be added to the vial to prepare a stock solution of 0.2 ug/ul. Centrifuge the vial at 4°C before opening to recover the entire contents.

Gene Information

• Gene Name: CDK1 cyclin-dependent kinase 1 [ Homo sapiens ]
• Official Symbol: CDK1
• Synonyms: CDK1; cyclin-dependent kinase 1; CDC2, cell division cycle 2, G1 to S and G2 to M; CDC28A; p34 protein kinase; cell cycle controller CDC2; cell division protein kinase 1; cell division control protein 2 homolog; cell division cycle 2, G1 to S and G2 to M; CDC2; P34CDC2; MGC111195; DKFZp686L20222
• Gene ID: 983
• mRNA Refseq: NM_001170406
• Protein Refseq: NP_001163877
• MIM: 116940
• UniProt ID: P06493

Reviews

01/30/2023

The product brochure is very detailed and has comprehensive basic information about the CDK1 protein.

11/09/2022

The staff actively communicated with me and solved many technical problems.

10/18/2022

Very professional customer service, fully understanding the needs of the customer and giving professional advice.

Q&As

What diseases is CDK1 involved in?

CDK1 is involved in papillary thyroid cancer, hepatocellular carcinoma, and other diseases.

How does CDK1 relate to IL-33 expression?

CDK1 is positively correlated with IL⁃33 expression and CDK1 and IL⁃33 expression interact with each other.

What is the function of CDK1?

CDK1 is an important regulator of the eukaryotic cell cycle that drives cell cycle progression by binding to cell cycle proteins.

What is the expression level of CDK1 in colorectal cancer?

CDK1 expression levels were higher in CRC tissues than in paracancerous tissues.