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Recombinant Human CDK20 protein, GST-tagged

Cat.No. : CDK20-01H
Product Overview : Full-length recombinant mouse CDK20 (CCRK) was expressed by baculovirus in Sf9 insect cells using an N-terminal GST tag.
  • Specification
  • Gene Information
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Description : CDK20 or cyclin-dependent kinase 20 contains a kinase domain most closely related to the cyclin-dependent protein kinases which may activate cyclin-dependent kinase 2 and is involved in cell growth. CDK20 is a monomeric CAK that specifically phosphorylates CDK2 thr160 and functions as a CDK2-activating kinase. CDK20 is also a novel cyclin-dependent kinase-activating kinase in mammalian cells. CDK20 depletion inhibits glioblastoma cell proliferation in a cilium-dependent manner.
Source : Insect cells
Species : Human
Tag : GST
Form : 50mM Tris-HCl, pH 7.5, 50mM NaCl, 10mM glutathione, 0.1mM EDTA, 0.25mM DTT, 0.1mM PMSF, 25% glycerol.
Molecular Mass : ~64 kDa
Purity : >80%
Applications : Western Blot
Stability : 1 year at -70 centigrade from date of shipment
Storage : Store product at –70 centigrade. For optimal storage, aliquot target into smaller quantities after centrifugation and store at recommended temperature. For most favorable performance, avoid repeated handling and multiple freeze/thaw cycles.
Concentration : 0.1 ug/uL
Gene Name : CDK20 cyclin-dependent kinase 20 [ Homo sapiens ]
Official Symbol : CDK20
Synonyms : CDK20; cyclin-dependent kinase 20; CCRK, cell cycle related kinase; p42; CAK-kinase p42; CDK-activating kinase p42; cell cycle-related kinase; cell division protein kinase 20; cyclin-dependent protein kinase H; cyclin-kinase-activating kinase p42; P42; CCRK; CDCH; PNQALRE;
Gene ID : 23552
mRNA Refseq : NM_001039803
Protein Refseq : NP_001034892
MIM : 610076
UniProt ID : Q8IZL9
Chromosome Location : 9q22.1
Function : ATP binding; cyclin-dependent protein kinase activity; nucleotide binding;

For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.

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