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Recombinant Human CEACAM6 protein, His & T7-tagged

Cat.No. : CEACAM6-8197H
Product Overview : Recombinant Human CEACAM6 aa. (Lys35~Pro142 (Accession # P40199)) fused with N-terminal His & T7 tag was produced in E. coli cells.
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  • Gene Information
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Description : This gene encodes a protein that belongs to the carcinoembryonic antigen (CEA) family whose members are glycosyl phosphatidyl inositol (GPI) anchored cell surface glycoproteins. Members of this family play a role in cell adhesion and are widely used as tumor markers in serum immunoassay determinations of carcinoma. This gene affects the sensitivity of tumor cells to adenovirus infection. The protein encoded by this gene acts as a receptor for adherent-invasive E. coli adhesion to the surface of ileal epithelial cells in patients with Crohn's disease. This gene is clustered with genes and pseudogenes of the cell adhesion molecules subgroup of the CEA family on chromosome 19.
Source : E. coli
Species : Human
Tag : His & T7
Form : Freeze-dried powder
Molecular Mass : Predicted Molecular Mass: 15.8kDa.
Protein length : Lys35~Pro142 (Accession # P40199)
Endotoxin : <1.0EU per 1ug (determined by the LAL method)
Purity : >95%
Characteristic : The isoelectric point is 6.5.
Applications : SDS-PAGE; WB; ELISA; IP.
Stability : The thermal stability is described by the loss rate of the target protein. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37°C for 48h, and no obvious degradation and precipitation were observed. (Referring from China Biological Products Standard, which was calculated by the Arrhenius equation.) The loss of this protein is less than 5% within the expiration date under appropriate storage condition.
Storage : Avoid repeated freeze/thaw cycles. Store at 2-8°C for one month. Aliquot and store at -80°C for 12 months.
Storage Buffer : Supplied as lyophilized form in PBS, pH7.4, containing 5% trehalose, 0.01% sarcosyl.
Reconstitution : Reconstitute in sterile PBS, pH7.2-pH7.4.
Gene Name : CEACAM6 carcinoembryonic antigen related cell adhesion molecule 6 [ Homo sapiens (human) ]
Official Symbol : CEACAM6
Synonyms : CEACAM6; carcinoembryonic antigen related cell adhesion molecule 6; NCA; CEAL; CD66c; carcinoembryonic antigen-related cell adhesion molecule 6; Cluster of Differentiation 66c; carcinoembryonic antigen-related cell adhesion molecule 6 (non-specific cross reacting antigen); normal cross-reacting antigen
Gene ID : 4680
mRNA Refseq : NM_002483.6
Protein Refseq : NP_002474.4
UniProt ID : P40199

For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.

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Q&As (5)

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How does CEACAM6 contribute to inflammation? 04/19/2022

CEACAM6 is involved in regulating the inflammatory response in the gut, making it relevant to inflammatory bowel disease.

Are there diagnostic tests for CEACAM6 in inflammatory bowel disease? 09/01/2020

CEACAM6 levels can be measured in clinical tests to assess inflammation in the gastrointestinal tract.

Can CEACAM6 be used for monitoring disease progression? 10/10/2018

Yes, CEACAM6 levels can be monitored to track the progression of certain diseases.

Are there therapeutic strategies targeting CEACAM6 in infections? 12/16/2017

Research is ongoing to develop therapies that inhibit CEACAM6 interactions with pathogens to prevent infection.

Is CEACAM6 protein used in immunotherapy for cancer? 03/02/2016

Some immunotherapeutic approaches involve targeting CEACAM6 to enhance the immune response against cancer cells.

Customer Reviews (3)

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Reviews
05/23/2022

    They provide a wealth of technical information and extensive documentation about the CEACAM6 protein, ensuring I have a comprehensive understanding of its characteristics, handling protocols, and storage requirements.

    11/13/2021

      the manufacturer ensures a streamlined supply chain management system to meet my trial's requirements.

      11/16/2020

        the manufacturer facilitates access to the latest scientific advancements and developments related to CEACAM6 protein research.

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