Recombinant Human CELF2 Protein, Myc/DDK-tagged, C13 and N15-labeled

• Cat.No.: CELF2-1404H
• Product Overview: CELF2 MS Standard C13 and N15-labeled recombinant protein (NP_001077060) with a C-terminal MYC/DDK tag, was expressed in HEK293 cells.

Specification

• Description: Members of the CELF/BRUNOL protein family contain two N-terminal RNA recognition motif (RRM) domains, one C-terminal RRM domain, and a divergent segment of 160-230 aa between the second and third RRM domains. Members of this protein family regulate pre-mRNA alternative splicing and may also be involved in mRNA editing, and translation. Alternative splicing results in multiple transcript variants encoding different isoforms.
• Source: HEK293
• Species: Human
• Tag: Myc/DDK
• Molecular Mass: 51.9 kDa
• AA Sequence: MNGALDHSDQPDPDAIKMFVGQIPR SWSEKELKELFEPYGAVYQINVLRD RSQNPPQSKGCCFVTFYTRKAALEA QNALHNIKTLPGMHHPIQMKPADSE KSNAVEDRKLFIGMVSKKCNENDIR VMFSPFGQIEECRILRGPDGLSRGC AFVTFSTRAMAQNAIKAMHQSQTME GCSSPIVVKFADTQKDKEQRRLQQQ LAQQMQQLNTATWGNLTGLGGLTPQ YLALLQQATSSSNLGAFSGIQQMAG MNALQLQNLATLAAAAAAAQTSATS TNANPLSTTSSALGALTSPVAASTP NSTAGAAMNSLTSLGTLQGLAGATV GLNNINALAGTINSMAALNGGLGAT GLTNGTAGTMDALTQAYSGIQQYAA AALPTLYSQSLLQQQSAAGSQKEGP EGANLFIYHLPQEFGDQDILQMFMP FGNVISAKVFIDKQTNLSKCFGFVS YDNPVSAQAAIQAMNGFQIGMKRLK VQLKRSKNDSKPYTRTRPLEQKLIS EEDLAANDILDYKDDDDKV
• Purity: > 80% as determined by SDS-PAGE and Coomassie blue staining
• Stability: Stable for 3 months from receipt of products under proper storage and handling conditions.
• Storage: Store at -80 centigrade. Avoid repeated freeze-thaw cycles.
• Concentration: 50 μg/mL as determined by BCA
• Storage Buffer: 100 mM glycine, 25 mM Tris-HCl, pH 7.3.

Gene Information

• Gene Name: CELF2 CUGBP Elav-like family member 2 [ Homo sapiens (human) ]
• Official Symbol: CELF2
• Synonyms: CELF2; CUGBP, Elav-like family member 2; CUG triplet repeat, RNA binding protein 2, CUG triplet repeat, RNA binding protein 2, CUGBP2; CUGBP Elav-like family member 2; BRUNOL3; Etr 3; NAPOR 2; CELF-2; hNAPOR; CUG-BP2; bruno-like protein 3; RNA-binding protein BRUNOL-3; CUG-BP- and ETR-3-like factor 2; ELAV-type RNA-binding protein 3; CUG triplet repeat RNA-binding protein 2; CUG triplet repeat, RNA binding protein 2; neuroblastoma apoptosis-related RNA-binding protein; ETR3; ETR-3; NAPOR; CUGBP2
• Gene ID: 10659
• mRNA Refseq: NM_001083591
• Protein Refseq: NP_001077060
• MIM: 602538
• UniProt ID: O95319