Recombinant Human CELSR1 Protein, His-tagged

Cat.No. : CELSR1-739H
Product Overview : Recombinant Human CELSR1 Protein (Pro246-Phe459) with His tag was expressed in E. coli.
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Species : Human
Source : E.coli
Tag : His
Protein Length : Pro246-Phe459
Description : The protein encoded by this gene is a member of the flamingo subfamily, part of the cadherin superfamily. The flamingo subfamily consists of nonclassic-type cadherins; a subpopulation that does not interact with catenins. The flamingo cadherins are located at the plasma membrane and have nine cadherin domains, seven epidermal growth factor-like repeats and two laminin A G-type repeats in their ectodomain. They also have seven transmembrane domains, a characteristic unique to this subfamily. It is postulated that these proteins are receptors involved in contact-mediated communication, with cadherin domains acting as homophilic binding regions and the EGF-like domains involved in cell adhesion and receptor-ligand interactions. This particular member is a developmentally regulated, neural-specific gene which plays an unspecified role in early embryogenesis.
Form : Freeze-dried powder
Molecular Mass : Predicted Molecular Mass: 28 kDa; Accurate Molecular Mass: 33 kDa
Purity : > 95%
Applications : Positive Control; Immunogen; SDS-PAGE; WB.
Stability : The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37 centigrade for 48h, and no obvious degradation and precipitation were observed. The loss rate is less than 5% within the expiration date under appropriate storage condition.
Storage : Avoid repeated freeze/thaw cycles. Store at 2-8 centigrade for one month. Aliquot and store at -80 centigrade for 12 months.
Storage Buffer : PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
Reconstitution : Reconstitute in PBS or others.
Gene Name CELSR1 cadherin EGF LAG seven-pass G-type receptor 1 [ Homo sapiens (human) ]
Official Symbol CELSR1
Synonyms CELSR1; cadherin EGF LAG seven-pass G-type receptor 1; ME2; FMI2; CDHF9; HFMI2; ADGRC1; LMPHM9; cadherin EGF LAG seven-pass G-type receptor 1; adhesion G protein-coupled receptor C1; cadherin family member 9; cadherin, EGF LAG seven-pass G-type receptor 1 (flamingo homolog, Drosophila); flamingo homolog 2; protocadherin flamingo 2
Gene ID 9620
mRNA Refseq NM_014246
Protein Refseq NP_055061
MIM 604523
UniProt ID Q9NYQ6

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