Recombinant Human CERKL Protein, Myc/DDK-tagged, C13 and N15-labeled

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Recombinant Human CERKL Protein, Myc/DDK-tagged, C13 and N15-labeled

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Cat.No. : CERKL-1547H
Product Overview : CERKL MS Standard C13 and N15-labeled recombinant protein (NP_963842) with a C-terminal MYC/DDK tag, was expressed in HEK293 cells.
Description : This gene was initially identified as a locus (RP26) associated with an autosomal recessive form of retinitis pigmentosa (arRP) disease. This gene encodes a protein with ceramide kinase-like domains, however, the protein does not phosphorylate ceramide and its target substrate is currently unknown. This protein may be a negative regulator of apoptosis in photoreceptor cells. Mutations in this gene cause a form of retinitis pigmentosa characterized by autosomal recessive cone and rod dystrophy (arCRD). Alternative splicing of this gene results in multiple transcript variants encoding different isoforms and non-coding transcripts.
Source : HEK293
Species : Human
Tag : Myc/DDK
Molecular Mass : 59.4 kDa
AA Sequence : MPWRRRRNRV SALEGGREEE APPEAAAVPP ALLTSPQQTE AAAERILLRG IFEIGRDSCD VVLSERALRW RPIQPERPAG DSKYDLLCKE EFIELKDIFS VKLKRRCSVK QQRSGTLLGI TLFICLKKEQ NKLKNSTLDL INLSEDHCDI WFRQFKKILA GFPNRPKSLK ILLNPQSHKK EATQVYYEKV EPLLKLAGIK TDVTIMEYEG HALSLLKECE LQGFDGVVCV GGDGSASEVA HALLLRAQKN AGMETDRILT PVRAQLPLGL IPAGSTNVLA HSLHGVPHVI TATLHIIMGH VQLVDVCTFS TAGKLLRFGF SAMFGFGGRT LALAEKYRWM SPNQRRDFAV VKALAKLKAE DCEISFLPFN SSDDVQERRA QGSPKSDCND QWQMIQGQFL NVSIMAIPCL CSVAPRGLAP NTRLNNGSMA LIIARNTSRP EFIKHLKRYA SVKNQFNFPF VETYTVEEVK VHPRNNTGGY NPEEEEDETA SENCFPWNVD GDLMEVASEV HIRLHPRLIS LYGGSMEEMI PKTRTRPLEQ KLISEEDLAA NDILDYKDDD DKV
Purity : > 80% as determined by SDS-PAGE and Coomassie blue staining
Stability : Stable for 3 months from receipt of products under proper storage and handling conditions.
Storage : Store at -80 centigrade. Avoid repeated freeze-thaw cycles.
Concentration : 50 μg/mL as determined by BCA
Storage Buffer : 100 mM glycine, 25 mM Tris-HCl, pH 7.3.
SDS-PAGE :

Gene Name : CERKL ceramide kinase-like [ Homo sapiens (human) ]
Official Symbol : CERKL
Synonyms : CERKL; ceramide kinase like; RP26; ceramide kinase-like protein;
Gene ID : 375298
mRNA Refseq : NM_201548
Protein Refseq : NP_963842
MIM : 608381
UniProt ID : Q49MI3
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.

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