| Description : |
This gene encodes a kinase that specifically phosphorylates the N-terminal region of the non-collagenous domain of the alpha 3 chain of type IV collagen, known as the Goodpasture antigen. Goodpasture disease is the result of an autoimmune response directed at this antigen. One isoform of this protein is also involved in ceramide intracellular transport. Three transcript variants encoding different isoforms have been found for this gene. |
| Source : |
HEK293 |
| Species : |
Human |
| Tag : |
Myc/DDK |
| Molecular Mass : |
67.8 kDa |
| AA Sequence : |
MSDNQSWNSSGSEEDPETESGPPVE RCGVLSKWTNYIHGWQDRWVVLKNN ALSYYKSEDETEYGCRGSICLSKAV ITPHDFDECRFDISVNDSVWYLRAQ DPDHRQQWIDAIEQHKTESGYGSES SLRRHGSMVSLVSGASGYSATSTSS FKKGHSLREKLAEMETFRDILCRQV DTLQKYFDACADAVSKDELQRDKVV EDDEDDFPTTRSDGDFLHSTNGNKE KLFPHVTPKGINGIDFKGEAITFKA TTAGILATLSHCIELMVKREDSWQK RLDKETEKKRRTEEAYKNAMTELKK KSHFGGPDYEEGPNSLINEEEFFDA VEAALDRQDKIEEQSQSEKVRLHWP TSLPSGDAFSSVGTHRFVQKVEEMV QNHMTYSLQDVGGDANWQLVVEEGE MKVYRREVEENGIVLDPLKATHAVK GVTGHEVCNYFWNVDVRNDWETTIE NFHVVETLADNAIIIYQTHKRVWPA SQRDVLYLSVIRKIPALTENDPETW IVCNFSVDHDSAPLNNRCVRAKINV AMICQTLVSPPEGNQEISRDNILCK ITYVANVNPGGWAPASVLRAVAKRE YPKFLKRFTSYVQEKTAGKPILFSG PTRTRRLEQKLISEEDLAANDILDY KDDDDKV |
| Purity : |
> 80% as determined by SDS-PAGE and Coomassie blue staining |
| Stability : |
Stable for 3 months from receipt of products under proper storage and handling conditions. |
| Storage : |
Store at -80 centigrade. Avoid repeated freeze-thaw cycles. |
| Concentration : |
50 μg/mL as determined by BCA |
| Storage Buffer : |
100 mM glycine, 25 mM Tris-HCl, pH 7.3. |
