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Recombinant Human CFD Protein, GST-tagged

Cat.No. : CFD-2554H
Product Overview : Human DF full-length ORF ( NP_001919.2, 1 a.a. - 253 a.a.) recombinant protein with GST-tag at N-terminal.
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  • Gene Information
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Description : This gene encodes a member of the S1, or chymotrypsin, family of serine peptidases. This protease catalyzes the cleavage of factor B, the rate-limiting step of the alternative pathway of complement activation. This protein also functions as an adipokine, a cell signaling protein secreted by adipocytes, which regulates insulin secretion in mice. Mutations in this gene underlie complement factor D deficiency, which is associated with recurrent bacterial meningitis infections in human patients. Alternative splicing of this gene results in multiple transcript variants. At least one of these variants encodes a preproprotein that is proteolytically processed to generate the mature protease. [provided by RefSeq, Nov 2015]
Source : Wheat Germ
Species : Human
Tag : GST
Molecular Mass : 53.4 kDa
AA Sequence : MHSWERLAVLVLLGAAACAAPPRGR ILGGREAEAHARPYMASVQLNGAHL CGGVLVAEQWVLSAAHCLEDAADGK VQVLLGAHSLSQPEPSKRLYDVLRA VPHPDSQPDTIDHDLLLLQLSEKAT LGPAVRPLPWQRVDRDVAPGTLCDV AGWGIVNHAGRRPDSLQHVLLPVLD RATCNRRTHHDGAITERLMCAESNR RDSCKGDSGGPLVCGGVLEGVVTSG SRVCGNRKKPGIYTRVASYAAWIDS VLA
Applications : Enzyme-linked Immunoabsorbent Assay
Western Blot (Recombinant protein)
Antibody Production
Protein Array
Notes : Best use within three months from the date of receipt of this protein.
Storage : Store at -80 centigrade. Aliquot to avoid repeated freezing and thawing.
Storage Buffer : 50 mM Tris-HCI, 10 mM reduced Glutathione, pH=8.0 in the elution buffer.
Gene Name : CFD complement factor D (adipsin) [ Homo sapiens ]
Official Symbol : CFD
Synonyms : CFD; complement factor D (adipsin); D component of complement (adipsin) , DF, PFD, properdin factor D; complement factor D; ADN; properdin factor D; C3 convertase activator; complement factor D preproprotein; D component of complement (adipsin); DF; PFD; ADIPSIN;
Gene ID : 1675
mRNA Refseq : NM_001928
Protein Refseq : NP_001919
MIM : 134350
UniProt ID : P00746

For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.

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