Recombinant Human CFTR protein, GST-tagged

Cat.No. : CFTR-275H
Product Overview : Recombinant Human CFTR fused with GST tag was expressed in E. coli.
Availability November 05, 2024
Unit
Price
Qty
  • Specification
  • Gene Information
  • Related Products
  • Download
Source : E. coli
Species : Human
Tag : GST
Form : 20 mM Tris-HCl, 0.15 M NaCl, pH 8.0
AA Sequence : MSPILGYWKIKGLVQPTRLLLEYLE EKYEEHLYERDEGDKWRNKKFELGL EFPNLPYYIDGDVKLTQSMAIIRYI ADKHNMLGGCPKERAEISMLEGAVL DIRYGVSRIAYSKDFETLKVDFLSK LPE
MLKMFEDRLCHKTYLNGDHVTHPDF MLYDALDVVLYMDPMCLDAFPKLVC FKKRIEAIPQIDKYLKSSKYIAWPL QGWQATFGGGDHPPKSDLVPRGSYQ IIRRTLKQAFADCTVILCEHRIEAM L
ECQQFLVIEENKVRQYDSIQKLLNE RSLFRQAISPSDRVKLFPHRNSSKC KSKPQIAALKEETEEEVQDTRL
Storage : For long term storage, prepare aliquots and store at -20 ~ -80 centigrade. Avoid freeze/thaw cycles.
Publication :
Cystic Fibrosis Transmembrane Conductance Regulator Attaches Tumor Suppressor PTEN to the Membrane and Promotes Anti Pseudomonas aeruginosa Immunity (2017)
Gene Name : CFTR cystic fibrosis transmembrane conductance regulator (ATP-binding cassette sub-family C, member 7) [ Homo sapiens ]
Official Symbol : CFTR
Synonyms : CFTR; cystic fibrosis transmembrane conductance regulator (ATP-binding cassette sub-family C, member 7); ABCC7, CF, cystic fibrosis transmembrane conductance regulator, ATP binding cassette (sub family C, member 7); cystic fibrosis transmembrane conductance regulator; ABC35; ATP binding cassette sub family C; member 7; CFTR/MRP; dJ760C5.1; MRP7; TNR CFTR; cAMP-dependent chloride channel; channel conductance-controlling ATPase; ATP-binding cassette sub-family C member 7; ATP-binding cassette transporter sub-family C member 7; CF; ABCC7; TNR-CFTR;
Gene ID : 1080
mRNA Refseq : NM_000492
Protein Refseq : NP_000483
MIM : 602421
UniProt ID : P13569
Chromosome Location : 7q31-q32
Pathway : ABC transporters, organism-specific biosystem; ABC transporters, conserved biosystem; ABC-family proteins mediated transport, organism-specific biosystem; Bile secretion, organism-specific biosystem; Bile secretion, conserved biosystem; Gastric acid secretion, organism-specific biosystem; Gastric acid secretion, conserved biosystem;
Function : ATP binding; ATP-binding and phosphorylation-dependent chloride channel activity; ATPase activity; PDZ domain binding; channel-conductance-controlling ATPase activity; chloride channel activity; enzyme binding; hydrolase activity; ion channel activity; nucleotide binding; protein binding;

For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.

Inquiry

  • Reviews
  • Q&As

Customer Reviews (3)

Write a review
Reviews
12/25/2020

    the CFTR protein's exceptional quality, coupled with the manufacturer's outstanding technical support, ensures that it fulfills my experimental needs with utmost precision and efficacy.

    05/08/2019

      the CFTR protein is an exceptional tool for investigating the intricate mechanisms and pathogenesis of amyloid-related diseases.

      01/09/2016

        Their collaboration during trial design and data analysis enhances the reliability and significance of my research findings.

        Q&As (5)

        Ask a question
        Is there any gene therapy or medications targeting CFTR protein for CF treatment? 10/22/2022

        Yes, there are medications like Ivacaftor, Lumacaftor, and Tezacaftor that target specific CFTR mutations to improve CFTR function. Gene therapy approaches are also being developed.

        Are there different types of CFTR mutations, and do they have varying clinical implications? 03/13/2021

        Yes, there are various types of CFTR mutations, some of which are associated with milder or more severe forms of CF, depending on the specific mutation.

        Are there ongoing clinical trials and research related to CFTR protein and CF treatment? 02/11/2021

        Yes, there are numerous clinical trials and research studies focusing on CFTR-targeted therapies and novel approaches for treating cystic fibrosis.

        Can CFTR protein-related therapies benefit individuals with non-CF conditions? 07/18/2019

        Yes, some CFTR-targeted therapies may have potential applications in conditions involving mucus secretion, like chronic bronchitis and bronchiectasis.

        What are the current clinical treatments for CF patients related to CFTR protein dysfunction? 02/04/2019

        Current treatments aim to alleviate symptoms and improve the quality of life for CF patients, including therapies to reduce mucus thickness, antibiotics for lung infections, and airway clearance techniques.

        Ask a Question for All CFTR Products

        Required fields are marked with *

        My Review for All CFTR Products

        Required fields are marked with *

        0

        Inquiry Basket

        cartIcon
        logo

        FOLLOW US

        Terms and Conditions        Privacy Policy

        Copyright © 2024 Creative BioMart. All Rights Reserved.

        Contact Us

        • /
        • Service lnquiry:

        Stay Updated on the Latest Bioscience Trends