Recombinant Human CHCHD3 Protein, GST-Tagged

• Cat.No.: CHCHD3-1208H
• Product Overview: Human CHCHD3 full-length ORF (NP_060282.1, 1 a.a. - 227 a.a.) recombinant protein with GST-tag at N-terminal.

Specification

• Description: The protein encoded by this gene is an inner mitochondrial membrane scaffold protein. Absence of the encoded protein affects the structural integrity of mitochondrial cristae and leads to reductions in ATP production, cell growth, and oxygen consumption. This protein is part of the mitochondrial contact site and cristae organizing system (MICOS). Several transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Nov 2015]
• Source: Wheat Germ
• Species: Human
• Tag: GST
• Molecular Mass: 52.6 kDa
• AA Sequence: MGGTTSTRRVTFEADENENITVVKG IRLSENVIDRMKESSPSGSKSQRYS GAYGASVSDEELKRRVAEELALEQA KKESEDQKRLKQAKELDRERAAANE QLTRAILRERICSEEERAKAKHLAR QLEEKDRVLKKQDAFYKEQLARLEE RSSEFYRVTTEQYQKAAEEVEAKFK RYESHPVCADLQAKILQCYRENTHQ TLKCSALATQYMHCVNHAKQSMLEK GG
• Applications: Enzyme-linked Immunoabsorbent Assay
  Western Blot (Recombinant protein)
  Antibody Production
  Protein Array
• Storage: Store at -80 centigrade. Aliquot to avoid repeated freezing and thawing.
• Storage Buffer: 50 mM Tris-HCI, 10 mM reduced Glutathione, pH=8.0 in the elution buffer.

Gene Information

• Gene Name: CHCHD3 coiled-coil-helix-coiled-coil-helix domain containing 3 [ Homo sapiens ]
• Official Symbol: CHCHD3
• Synonyms: CHCHD3; coiled-coil-helix-coiled-coil-helix domain containing 3; coiled-coil-helix-coiled-coil-helix domain-containing protein 3, mitochondrial; FLJ20420; MINOS3; mitochondrial inner membrane organizing system 3; PPP1R22; protein phosphatase 1; regulatory subunit 22; protein phosphatase 1, regulatory subunit 22
• Gene ID: 54927
• mRNA Refseq: NM_017812
• Protein Refseq: NP_060282
• MIM: 613748
• UniProt ID: Q9NX63