Recombinant Human CHD7 Protein, His-tagged

• Cat.No.: CHD7-32H
• Product Overview: Partial recombinant protein (Ala685-Asn988) of human CHD7 (Chromodomain Helicase DNA Binding Protein 7). Expressed in E. coli with N-terminal His tag.

Specification

• Species: Human
• Source: E. coli
• Tag: His
• Protein Length: Ala685-Asn988 aa (304 aa)
• Description: CHD7 (Chromodomain Helicase DNA Binding Protein 7) is an ATP-dependent chromatin remodeling enzyme that contains multiple chromodomains and helicase domains. Mutations in CHD7 are associated with CHARGE syndrome (Coloboma, Heart defects, Atresia of choanae, Retarded growth, Genital hypoplasia, Ear anomalies). CHD7 plays critical roles in embryonic development, neural crest cell migration, and regulation of gene expression through chromatin remodeling.
• Form: Liquid
• Molecular Mass: 35.6 kDa
• Purity: > 80% as determined by SDS-PAGE and Coomassie blue staining
• Notes: For testing in cell culture applications, please filter before use. Note that you may experience some loss of protein during the filtration process.
• Storage: Store at -80°C. Stable for 12 months. Avoid repeated freeze-thaw cycles.
• Concentration: >0.05 ug/uL as determined by microplate BCA method
• Storage Buffer: 50 mM Tris-HCl, pH 8.0, 8 M urea

Gene Information

• Gene Name: CHD7
• Official Symbol: CHD7
• Synonyms: CRG; HH5; IS3; KAL5
• Gene ID: 55636
• mRNA Refseq: NM_017780
• Protein Refseq: NP_060250
• MIM: 608892
• UniProt ID: Q9P2D1