Recombinant Human Chemokine (C-C motif) Ligand 27

• Cat.No.: CCL27-76H
• Product Overview: Recombinant Human Chemokine (C-C motif) Ligand 27 was expressed inE. Coli.

Specification

• Cat. No.: CCL27-76H
• Description: Human CTAC (Cuteaneous T-Cell Attracting Chemokine) is also known as Skinkine, Eskine and CCL27. CTAC is predominantly expressed in the skin and selectively attracts skin-associated memory T-lymphocytes. Recombinant Human CTAC is a 9.8 kDa protein containing 86 amino acid residues.
• Source: E. Coli.
• Note: If this material is not to be used for coating or labeling (or other applications requiring carrier free material), the addition of 0.1% BSA or HSA to dilution buffers or dilution in sterile culture media is recommended to enhance stability and minimize absorption to vial. Ideally, maintain stock >20ug/ml.
• Reactivity: Determined by its ability to chemoattract CXCR3 transfected cells using a concentration of 10.0-100.0ng/ml.
• Purity: >98% by SDS-Page analysis. Endotoxin level is less than 0.1ng per ug (1EU/ug) of protein.
• Reconstitution: Lyophilized CTAC should be reconstituted in water to a concentration of 0.1-1mg/ml. Allow to set at least 30 minutes at 4°C, mix well. If desired, tighten cap and centrifuge for 1 minute at 1000rpm to concentrate material in vial. This solution can be diluted into other buffered solutions or stored at 4 °C for up to 1 week or at -20 °C for future use.
• Storage: The lyophilized powder is stable at room temperature for a few weeks but it is best stored desiccated at -20°C. Reconstituted CTAC should be stored in working aliquots at -20 °C. AVOID FREQUENT FREEZE THAW CYCLES.
• Supplied: Lyophilized powder with no additives.

Gene Information

• Gene Name: chemokine (C-C motif) ligand 27 [Homo sapiens]
• Synonyms: chemokine (C-C motif) ligand 27; ALP; ILC; CTAK; CTACK; PESKY; ESKINE; SCYA27; CCL27; small inducible cytokine A27; skinkine; CC chemokine ILC; IL-11 Ralpha-locus chemokine; cutaneous T-cell attracting chemokine; small inducible cytokine subfamily A (Cys-Cys), member 27; skinkine; ESkine; IL-11 R-alpha-locus chemokine; Cutaneous T-cell-attracting chemokine; Small-inducible cytokine A27; Skinkine; OTTHUMP00000000533; OTTHUMP00000021297
• Gene ID: 10850
• mRNA Refseq: NM_006664
• Protein Refseq: NP_006655
• MIM: 604833
• UniProt ID: Q9Y4X3
• Chromosome Location: 9p13
• Pathway: Chemokine signaling pathway; Cytokine-cytokine receptor interaction; Signaling by GPCR
• Function: chemokine activity