Recombinant Human Chemokine (C-C Motif) Ligand 4-like 1 , His-tagged

• Cat.No.: CCL4L1-170H
• Product Overview: Recombinant human CCL4L1 protein, fused to His-tag at N-terminus, was expressed in E.coliand purified by conventional chromatography, after refolding of the isolated inclusion bodies in a renaturation buffer(24-92 aa).

Specification

• Species: Human
• Source: E.coli
• Tag: His
• Description: CCL4L1 (C-C motif chemokine 4-like) belongs to intercrine beta (chemokine CC) family. This protein is similar to CCL4 which inhibits HIV replication in peripheral blood monocytes that express CCR5.
• Form: Liquid. In 10mM sodium citrate (pH 3.5), 10% glycerol
• Molecular Weight: 10.5kDa (94aa) confirmed by MALDI-TOF (Molecular weight on SDS-PAGE will appear higher)
• Purity: > 90% by SDS - PAGE
• Concentration: 0.5mg/ml (determined by Bradford assay)
• Endotoxin Level: < 1.0 EU per 1 μg of protein (determined by LAL method )
• Sequences of amino acids: MGSSHHHHHH SSGLVPRGSH MGSHMAPMGS DPPTACCFSY TARKLPRNFV VDYYETSSLC SQPAVVFQTK RGKQVCADPS ESWVQEYVYD LELN
• Storage: Can be stored at +4°C short term (1-2 weeks). For long term storage, aliquot and store at -20°C or -70°C. Avoid repeated freezing and thawing cycles.

Gene Information

• Gene Name: CCL4L1 chemokine (C-C motif) ligand 4-like 1 [ Homo sapiens ]
• Synonyms: chemokine (C-C motif) ligand 4-like 1; LAG1; CCL4L; LAG-1; CCL4L2; SCYA4L; AT744.2; CCL4L1; C-C motif chemokine 4-like;MIP-1-beta;macrophage inflammatory protein-1b2;lymphocyte activation gene 1 protein;macrophage inflammatory protein 1-beta;monocyte adherence-induced protein 5-alpha; small inducible cytokine A4-like; chemokine (C-C motif) ligand 4-like; MIP-1-beta
• Gene ID: 9560
• mRNA Refseq: NM_001001435
• Protein Refseq: NP_001001435
• MIM: 603782
• UniProt ID: Q8NHW4
• Chromosome Location: 17q12
• Pathway: Chemokine signaling pathway, organism-specific biosystem; Chemokine signaling pathway, conserved biosystem; Cytokine-cytokine receptor interaction, organism-specific biosystem; Cytokine-cytokine receptor interaction, conserved biosystem; Cytosolic DNA-sensing pathway, organism-specific biosystem; Cytosolic DNA-sensing pathway, conserved biosystem; IL12-mediated signaling events, organism-specific biosystem
• Function: chemokine activity