Recombinant Human Chemokine (C-C Motif) Ligand 5

• Cat.No.: CCL5-125H

Specification

• Species: Human
• Source: Mammalian Cells
• Tag: Non
• Description: RANTES also known as Chemokine (C-C motif) ligand 5 (CCL5), a CC-chemokine is an important mediators of the immune and inflammatory response. It is also a potent chemoattractant for T cells and eosinophils. RANTES is involved in many inflammatory diseases, for example, bronchial asthma, delayed-type hypersensitivity reactions, viral infections, arthritis, chronic eosinophilic pneumonia, and idiopathic interstitial pneumonia.
• State Of Matter: Lyophilized.
• Purity: >90% by SDS Page and analyzed by silver stain.
• Endotoxin: <1.0 EU/µg as determined by the LAL method.
• Molecular Weight: The predicted molecular weight of Recombinant Human RANTES is Mr 34 kDa. However, the actual molecular weight as observed by migration on SDS Page is Mr 85-105 kDa.
• Storage And Stability: This lyophilized protein is stable for six to twelve months when stored desiccated at -20°C to -70°C. After aseptic reconstitution, this protein may be stored at 2°C to 8°C for one month or at -20°C to -70°C in a manual defrost freezer. Avoid Repeated Freeze Thaw Cycles.

Gene Information

• Gene Name: CCL5 chemokine (C-C motif) ligand 5 [ Homo sapiens ]
• Synonyms: CCL5; chemokine (C-C motif) ligand 5; SISd; beta-chemokine RANTES; EoCP; RANTES; TCP228; MGC17164; SCYA5; RANTES; TCP228; D17S136E; MGC17164; chemokine (C-C motif) ligand 5; regulated upon activation; normally T-expressed; and presumably secrete; presumably secreted; small inducible cytokine A5; small inducible cytokine A5 (RANTES); small inducible cytokine subfamily A (Cys-Cys); member 5; Small-inducible cytokine A5; Small-inducible cytokine A5; T cell-specific protein P228; Eosinophil-chemotactic cytokine; RANTES(3-68); RANTES(4-68); T-cell specific RANTES protein; T-cell-specific protein RANTES; SIS-delta
• Gene ID: 6352
• mRNA Refseq: NM_002985
• Protein Refseq: NP_002976
• MIM: 187011
• UniProt ID: P13501
• Chromosome Location: 17q11.2-q12
• Pathway: Chemokine signaling pathway; Cytokine-cytokine receptor interaction; Epithelial cell signaling in Helicobacter pylori infection; Prion diseases; Toll-like receptor signaling pathway; Signaling by GPCR
• Function: chemoattractant activity; chemokine activity; signal transducer activity