Recombinant Human CHIT1 Protein, MYC/DDK-tagged

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Recombinant Human CHIT1 Protein, MYC/DDK-tagged

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Cat.No. : CHIT1-3212H
Product Overview : Recombinant Human CHIT1 protein, fused to MYC/DDK-tagged at C-terminus, was expressed in HEK293.
Description : Chitotriosidase is secreted by activated human macrophages and is markedly elevated in plasma of Gaucher disease patients. The expression of chitotriosidase occurs only at a late stage of differentiation of monocytes to activated macrophages in culture. Human macrophages can synthesize a functional chitotriosidase, a highly conserved enzyme with a strongly regulated expression. This enzyme may play a role in the degradation of chitin-containing pathogens. Several alternatively spliced transcript variants have been described for this gene.
Source : HEK293
Species : Human
Tag : MYC/DDK
Form : 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol.
Molecular Mass : 51.5 kDa
Purity : > 80% as determined by SDS-PAGE and Coomassie blue staining
Concentration : >50 ug/mL as determined by microplate BCA method
Gene Name : CHIT1 chitinase 1 (chitotriosidase) [ Homo sapiens ]
Official Symbol : CHIT1
Synonyms : CHI3; CHIT; CHITD
Gene ID : 1118
mRNA Refseq : NM_001256125
Protein Refseq : NP_001243054
MIM : 600031
UniProt ID : Q13231

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