Recombinant Human CHMP5, GST-tagged
Cat.No. : | CHMP5-11189H |
Product Overview : | Recombinant Human CHMP5 protein, fused to GST-tag, was expressed in E.coli and purified by GSH-sepharose. |
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Description : | CHMP5 belongs to the chromatin-modifying protein/charged multivesicular body protein (CHMP) family. These proteins are components of ESCRT-III (endosomal sorting complex required for transport III), a complex involved in degradation of surface receptor proteins and formation of endocytic multivesicular bodies (MVBs). Some CHMPs have both nuclear and cytoplasmic/vesicular distributions, and one such CHMP, CHMP1A (MIM 164010), is required for both MVB formation and regulation of cell cycle progression (Tsang et al., 2006 [PubMed 16730941]). |
Source : | E.coli |
Species : | Human |
Tag : | GST |
Protein length : | 1-219a.a. |
Storage : | The protein is stored in PBS buffer at -20℃. Avoid repeated freezing and thawing cycles. |
Storage Buffer : | 1M PBS (58mM Na2HPO4,17mM NaH2PO4, 68mM NaCl, pH8. ) added with 100mM GSH and 1% Triton X-100,15%glycerol. |
Gene Name : | CHMP5 charged multivesicular body protein 5 [ Homo sapiens ] |
Official Symbol : | CHMP5 |
Synonyms : | CHMP5; charged multivesicular body protein 5; C9orf83, chromatin modifying protein 5 , chromosome 9 open reading frame 83 , SNF7DC2; CGI 34; HSPC177; Vps60; hVps60; SNF7 domain containing 2; chromatin modifying protein 5; chromatin-modifying protein 5; SNF7 domain-containing protein 2; apoptosis-related protein PNAS-2; vacuolar protein sorting-associated protein 60; CGI-34; PNAS-2; C9orf83; SNF7DC2; |
Gene ID : | 51510 |
mRNA Refseq : | NM_001195536 |
Protein Refseq : | NP_001182465 |
MIM : | 610900 |
UniProt ID : | Q9NZZ3 |
Chromosome Location : | 9p13.3 |
Pathway : | ESCRT-III complex, organism-specific biosystem; Endocytosis, organism-specific biosystem; Endocytosis, conserved biosystem; Endosomal Sorting Complex Required For Transport (ESCRT), organism-specific biosystem; Membrane Trafficking, organism-specific biosystem; |
Function : | protein binding; |
Products Types
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◆ Lysates | ||
CHMP5-7530HCL | Recombinant Human CHMP5 293 Cell Lysate | +Inquiry |
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For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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