Recombinant Human CIAO2A Protein, Myc/DDK-tagged, C13 and N15-labeled

• Cat.No.: CIAO2A-2095H
• Product Overview: FAM96A MS Standard C13 and N15-labeled recombinant protein (NP_115607) with a C-terminal MYC/DDK tag, was expressed in HEK293 cells.

Specification

• Description: Component of the cytosolic iron-sulfur protein assembly (CIA) complex, a multiprotein complex that mediates the incorporation of iron-sulfur cluster into extramitochondrial Fe/S proteins. As a CIA complex component and in collaboration with CIAO1 specifically matures ACO1 and stabilizes IREB2, connecting cytosolic iron-sulfur protein maturation with cellular iron regulation. May play a role in chromosome segregation through establishment of sister chromatid cohesion. May induce apoptosis in collaboration with APAF1.
• Source: HEK293
• Species: Human
• Tag: Myc/DDK
• Molecular Mass: 18.4 kDa
• AA Sequence: MQRVSGLLSWTLSRVLWLSGLSEPG AARQPRIMEEKALEVYDLIRTIRDP EKPNTLEELEVVSESCVEVQEINEE EYLVIIRFTPTVPHCSLATLIGLCL RVKLQRCLPFKHKLEIYISEGTHST EEDINKQINDKERVAAAMENPNLRE IVEQCVLEPDTRTRPLEQKLISEED LAANDILDYKDDDDKV
• Purity: > 80% as determined by SDS-PAGE and Coomassie blue staining
• Stability: Stable for 3 months from receipt of products under proper storage and handling conditions.
• Storage: Store at -80 centigrade. Avoid repeated freeze-thaw cycles.
• Concentration: 50 μg/mL as determined by BCA
• Storage Buffer: 100 mM glycine, 25 mM Tris-HCl, pH 7.3.

Gene Information

• Gene Name: CIAO2A cytosolic iron-sulfur assembly component 2A [ Homo sapiens (human) ]
• Official Symbol: CIAO2A
• Synonyms: CIAO2A; cytosolic iron-sulfur assembly component 2A; CIA2A; FAM96A; cytosolic iron-sulfur assembly component 2A; MIP18 family protein FAM96A; family with sequence similarity 96 member A
• Gene ID: 84191
• mRNA Refseq: NM_032231
• Protein Refseq: NP_115607
• MIM: 618382
• UniProt ID: Q9H5X1