Recombinant Human CLCNKB Protein, GST-tagged

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Recombinant Human CLCNKB Protein, GST-tagged

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Cat.No. : CLCNKB-1423H
Product Overview : Human CLCNKB full-length ORF ( AAH20873.1, 1 a.a. - 462 a.a.) recombinant protein with GST-tag at N-terminal.
Description : The protein encoded by this gene is a member of the family of voltage-gated chloride channels. Chloride channels have several functions, including the regulation of cell volume, membrane potential stabilization, signal transduction and transepithelial transport. This gene is expressed predominantly in the kidney and may be important for renal salt reabsorption. Mutations in this gene are associated with autosomal recessive Bartter syndrome type 3 (BS3). Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Sep 2009]
Source : Wheat Germ
Species : Human
Tag : GST
Molecular Mass : 77 kDa
AA Sequence : MEEFVGLREG SSGNPVTLQE LWGPCPRIRR GIRGGLEWLK QKLFRLGEDW YFLMTLGVLM ALVSCAMDLA VESVVRAHQW LYREIGDSHL LRYLSWTVYP VALVSFSSGF SQSITPSSGG SGIPEVKTML AGVVLEDYLD IKNFGAKVVG LSCTLACGST LFLGKVGPFV HLSVMMAAYL GRVRTTTIGE PENKSKPVYS ALATLVLASI TYPPSAGRFL ASRLSMKQHL DSLFDNHSWA LMTQNSSPPW PEELDPQHLW WEWYHPRFTI FGTLAFFLVM KFWMLILATT IPMPAGYFMP IFVYGAAIGR LFGETLSFIF PEGIVAGGIT NPIMPGGYAL AGAAAFSGAV THTISTALLA FEVTGQIVHA LPVLMAVLAA NAIAQSCQPS FYDGTVIVKK LPYLPRILGR NIGSHRVRVE HFMNHSITTL AITLMNDEIG VHCHQGQAQM ASGVVWFPVR GS
Applications : Enzyme-linked Immunoabsorbent Assay
Western Blot (Recombinant protein)
Antibody Production
Protein Array
Notes : Best use within three months from the date of receipt of this protein.
Storage : Store at -80 centigrade. Aliquot to avoid repeated freezing and thawing.
Storage Buffer : 50 mM Tris-HCI, 10 mM reduced Glutathione, pH=8.0 in the elution buffer.
Quality Control Testing: :

12.5% SDS-PAGE Stained with Coomassie Blue.

Gene Name : CLCNKB chloride channel, voltage-sensitive Kb [ Homo sapiens ]
Official Symbol : CLCNKB
Synonyms : CLCNKB; chloride channel, voltage-sensitive Kb; chloride channel Kb; chloride channel protein ClC-Kb; hClC Kb; chloride channel, kidney, B; CLCKB; ClC-K2; ClC-Kb; MGC24087;
Gene ID : 1188
mRNA Refseq : NM_000085
Protein Refseq : NP_000076
MIM : 602023
UniProt ID : P51801

Products Types

◆ Recombinant Protein

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For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.

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