Recombinant Human CLDN19 Protein, MYC/DDK-tagged

• Cat.No.: CLDN19-3245H
• Product Overview: Recombinant Human CLDN19 protein, fused to MYC/DDK-tagged at C-terminus, was expressed in HEK293.

Specification

• Description: The product of this gene belongs to the claudin family. It plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity. Defects in this gene are the cause of hypomagnesemia renal with ocular involvement (HOMGO). HOMGO is a progressive renal disease characterized by primary renal magnesium wasting with hypomagnesemia, hypercalciuria and nephrocalcinosis associated with severe ocular abnormalities such as bilateral chorioretinal scars, macular colobomata, significant myopia and nystagmus. Alternatively spliced transcript variants encoding distinct isoforms have been identified for this gene.
• Source: HEK293
• Species: Human
• Tag: MYC/DDK
• Form: 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol.
• Molecular Mass: 21.9 kDa
• Purity: > 80% as determined by SDS-PAGE and Coomassie blue staining
• Concentration: >50 ug/mL as determined by microplate BCA method

Gene Information

• Gene Name: CLDN19 claudin 19 [ Homo sapiens ]
• Official Symbol: CLDN19
• Synonyms: HOMG5; HOMG5
• Gene ID: 30063
• mRNA Refseq: NM_001123395.1
• Protein Refseq: NP_001116867.1
• MIM: 610036
• UniProt ID: Q8N6F1