Recombinant Human CLDN6 Protein, GST-tagged CLDN6-1445H

Recombinant Human CLDN6 Protein, GST-tagged

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Recombinant Human CLDN6 Protein, GST-tagged

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Cat.No. : CLDN6-1445H
Product Overview : Human CLDN6 full-length ORF ( NP_067018.1, 1 a.a. - 220 a.a.) recombinant protein with GST-tag at N-terminal.
Description : Tight junctions represent one mode of cell-to-cell adhesion in epithelial or endothelial cell sheets, forming continuous seals around cells and serving as a physical barrier to prevent solutes and water from passing freely through the paracellular space. These junctions are comprised of sets of continuous networking strands in the outwardly facing cytoplasmic leaflet, with complementary grooves in the inwardly facing extracytoplasmic leaflet. This gene encodes a component of tight junction strands, which is a member of the claudin family. The protein is an integral membrane protein and is one of the entry cofactors for hepatitis C virus. The gene methylation may be involved in esophageal tumorigenesis. This gene is adjacent to another family member CLDN9 on chromosome 16.[provided by RefSeq, Aug 2010]
Source : Wheat Germ
Species : Human
Tag : GST
Molecular Mass : 49.7 kDa
AA Sequence : MASAGMQILGVVLTL LGWVNGLVSCALPMW KVTAFIGNSIVVAQV VWEGLWMSCVVQSTG QMQCKVYDSLLALPQ DLQAARALCVIALLV ALFGLLVYLAGAKCT TCVEEKDSKARLVLT SGIVFVISGVLTLIP VCWTAHAVIRDFYNP LVAEAQKRELGASLY LGWAASGLLLLGGGL LCCTCPSGGSQGPSH YMARYSTSAPAISRG PSEYPTKNYV
Applications : Enzyme-linked Immunoabsorbent Assay
Western Blot (Recombinant protein)
Antibody Production
Protein Array
Notes : Best use within three months from the date of receipt of this protein.
Storage : Store at -80 centigrade. Aliquot to avoid repeated freezing and thawing.
Storage Buffer : 50 mM Tris-HCI, 10 mM reduced Glutathione, pH=8.0 in the elution buffer.
Quality Control Testing: :

12.5% SDS-PAGE Stained with Coomassie Blue.

Gene Name : CLDN6 claudin 6 [ Homo sapiens ]
Official Symbol : CLDN6
Synonyms : CLDN6; claudin 6; claudin-6; skullin;
Gene ID : 9074
mRNA Refseq : NM_021195
Protein Refseq : NP_067018
MIM : 615798
UniProt ID : P56747

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