Recombinant Human CLEC4C Protein, His-tagged

• Cat.No.: CLEC4C-026H
• Product Overview: Recombinant Human CLEC4C Protein with His tag was expressed in E. coli.

Specification

• Description: Lectin-type cell surface receptor which may play a role in antigen capturing by dendritic cells. Specifically recognizes non-sialylated galactose-terminated biantennary glycans containing the trisaccharide epitope Gal(beta1-3/4)GlcNAc(beta1-2)Man. Binds to serum IgG. Efficiently targets ligand into antigen-processing and peptide-loading compartments for presentation to T-cells. May mediate potent inhibition of induction of IFN-alpha/beta expression in plasmacytoid dendritic cells. May act as a signaling receptor that activates protein-tyrosine kinases and mobilizes intracellular calcium.
• Source: E. coli
• Species: Human
• Tag: His
• Molecular Mass: ~23 kDa
• AA Sequence: NFMYSKTVKRLSKLREYQQYHPSLT CVMEGKDIEDWSCCPTPWTSFQSSC YFISTGMQSWTKSQKNCSVMGADLV VINTREEQDFIIQNLKRNSSYFLGL SDPGGRRHWQWVDQTPYNENVTFWH SGEPNNLDERCAIINFRSSEEWGWN DIHCHVPQKSICKMKKIYI
• Purity: Transferred into competent cells and the supernatant was purified by NI column affinity chromatography and the purity is > 85% (by SDS-PAGE).
• Notes: For research use only, not for use in diagnostic procedure.
• Storage: Store at 4 centigrade short term. Aliquot and store at -20 centigrade long term. Avoid freeze-thaw cycles.
• Storage Buffer: PBS, 4M Urea, pH7.4

Gene Information

• Gene Name: CLEC4C C-type lectin domain family 4, member C [ Homo sapiens (human) ]
• Official Symbol: CLEC4C
• Synonyms: DLEC; HECL; BDCA2; CD303; CLECSF7; CLECSF11; PRO34150
• Gene ID: 170482
• mRNA Refseq: NM_203503
• Protein Refseq: NP_987099
• MIM: 606677
• UniProt ID: Q8WTT0