Recombinant Human CNOT2 Protein, His-tagged

• Cat.No.: CNOT2-190H
• Product Overview: Recombinant Human CNOT2 fused with His tag at N-terminal was expressed in E. coli.

Specification

• Species: Human
• Source: E.coli
• Tag: His
• Description: THis gene encodes a subunit of the multi-component CCR4-NOT complex. The CCR4-NOT complex regulates mRNA synthesis and degradation and is also thought to be involved in mRNA splicing, transport and localization. The encoded protein interacts with Histone deacetylases and functions as a repressor of polymerase II transcription. Alternatively spliced transcript variants have been observed for tHis gene.
• Form: 25mM Tris, pH8.0, 150 mM NaCl, 10% glycerol, 1 % Sarkosyl. Store at -80 centigrade. Avoid repeated freeze-thaw cycles. Stable for at least 3 months from receipt of products under proper storage and handling conditions.
• Molecular Mass: 59.7 kDa
• Purity: > 80% as determined by SDS-PAGE and Coomassie blue staining
• Concentration: >50 ug/mL as determined by microplate BCA method

Gene Information

• Gene Name: CNOT2 CCR4-NOT transcription complex, subunit 2 [ Homo sapiens ]
• Official Symbol: CNOT2
• Synonyms: CNOT2; CCR4-NOT transcription complex, subunit 2; NOT2; CCR4-NOT transcription complex subunit 2; CDC36; NOT2H; CCR4-associated factor 2; negative regulator of transcription 2; HSPC131; FLJ26456
• Gene ID: 4848
• mRNA Refseq: NM_001199302
• Protein Refseq: NP_001186231
• MIM: 604909
• UniProt ID: Q9NZN8