| Description : |
This gene encodes a protein that contains WH2 domains (WASP, Wiskott-Aldrich syndrome protein, homology domain-2) that interact with actin. The encoded actin regulator protein is required for growth and assembly of brush border microvilli that play a role in maintaining intestinal homeostasis. A similar protein in mouse functions in midbrain neural tube closure. A pseudogene of this gene is located on chromosome X. |
| Source : |
HEK293 |
| Species : |
Human |
| Tag : |
Myc/DDK |
| Molecular Mass : |
135.4 kDa |
| AA Sequence : |
MDAPRASAAKPPTGRKMKARAPPPP GKAATLHVHSDQKPPHDGALGSQQN LVRMKEALRASTMDVTVVLPSGLEK RSVLNGSHAMMDLLVELCLQNHLNP SHHALEIRSSETQQPLSFKPNTLIG TLNVHTVFLKEKVPEEKVKPGPPKV PEKSVRLVVNYLRTQKAVVRVSPEV PLQNILPVICAKCEVSPEHVVLLRD NIAGEELELSKSLNELGIKELYAWD NRRETFRKSSLGNDETDKEKKKFLG FFKVNKRSNSKGCLTTPNSPSMHSR SLTLGPSLSLGSISGVSVKSEMKKR RAPPPPGSGPPVQDKASEKVSLGSQ IDLQKKKRRAPAPPPPQPPPPSPLI PNRTEDKEENRKSTMVSLPLGSGSH CSPDGAPQVLSEAEETVSVGSCFAS EDTTEDSGVMSSPSDIVSLDSQQDS MKYKDKWATDQEDCSDQDLAGTPDL GPQKSPLWEKNGSENSHLRTEKAVT ASNDEEDLLIAGEFRKTLAELDEDL EEMEDSYETDTSSLTSSIHGASNHC PQDAMIPHGDTDAIPVTFIGEVSDD PVDSGLFSNRNNNAGSFDSEGVASR RDSLAPLQAEHSQPHEKAREEVPAL HPASHDVGKGIRVALSNISKDGNLM ETAPRVTSFASNLHTDNLNAKVKDK VYGCADGERTQATERVNSQPVNEKD SNDKNAALAPTSWHQRGQNPGKSYR LKHGLTTYKIIPPKSEMRCYDRDVS LSTGAIKIDELGNLVSPHATGIRII SLSSSVPEAESQPIGKVREFWRCNS VEKHLGRPSESSARGPPSTPVPTQT QNPESRLQADPKPISPQQKSAHHEG RNPLGEGRNQPPTMGMGHVRVPAAH TTEVTFLKPQRRTSSQYVASAIAKR IGAPKVHADVVRPHGYAEKGYAGKA PVLAAPPVTVKDDRTSSPHSETQGW KDGAQWPCVTPPNNHGEDLAVGAPP RGEVIGPHRKLSTQDRPAAIHRSSC FSLVQSSQRDRVSVGQSCGFSGKQS TSSQEASSASEPRRAPDGTDPPPPH TSDTQACSRELVNGSVRAPGHGEPS HPPGGSGTESHILLEREEKPSVFST DGNETDSIWPPSIFGPKKKFKPVVQ RPVPKDTSLHSALMEAIHSAGGKDR LRKTAEHTGEGRPAKLSYTEAEGER SALLAAIRGHSGTCSLRKVASSASE ELQSFRDAALSAQGSESPLLEDLGL LSPPAIPPPPPPPSQALSAPRTASR FSTGTLSNTADARQALMDAIRSGTG AARLRKVPLLVSGPTRTRRLEQKLI SEEDLAANDILDYKDDDDKV |
| Purity : |
> 80% as determined by SDS-PAGE and Coomassie blue staining |
| Stability : |
Stable for 3 months from receipt of products under proper storage and handling conditions. |
| Storage : |
Store at -80 centigrade. Avoid repeated freeze-thaw cycles. |
| Concentration : |
50 μg/mL as determined by BCA |
| Storage Buffer : |
100 mM glycine, 25 mM Tris-HCl, pH 7.3. |
