Recombinant Human COL5A3 Protein, GST-tagged

• Cat.No.: COL5A3-1658H
• Product Overview: Human COL5A3 partial ORF ( NP_056534, 157 a.a. - 244 a.a.) recombinant protein with GST-tag at N-terminal.

Specification

• Description: This gene encodes an alpha chain for one of the low abundance fibrillar collagens. Fibrillar collagen molecules are trimers that can be composed of one or more types of alpha chains. Type V collagen is found in tissues containing type I collagen and appears to regulate the assembly of heterotypic fibers composed of both type I and type V collagen. This gene product is closely related to type XI collagen and it is possible that the collagen chains of types V and XI constitute a single collagen type with tissue-specific chain combinations. Mutations in this gene are thought to be responsible for the symptoms of a subset of patients with Ehlers-Danlos syndrome type III. Messages of several sizes can be detected in northern blots but sequence information cannot confirm the identity of the shorter messages. [provided by RefSeq, Jul 2008]
• Source: Wheat Germ
• Species: Human
• Tag: GST
• Molecular Mass: 35.42 kDa
• AA Sequence: EMVTLVADCEAQPPVLGHGPRFISI AGLTVLGTQDLGEKTFEGDIQELLI SPDPQAAFQACERYLPDCDNLAPAA TVAPQGEPETPRP
• Applications: Enzyme-linked Immunoabsorbent Assay
  Western Blot (Recombinant protein)
  Antibody Production
  Protein Array
• Notes: Best use within three months from the date of receipt of this protein.
• Storage: Store at -80 centigrade. Aliquot to avoid repeated freezing and thawing.
• Storage Buffer: 50 mM Tris-HCI, 10 mM reduced Glutathione, pH=8.0 in the elution buffer.

Gene Information

• Gene Name: COL5A3 collagen, type V, alpha 3 [ Homo sapiens ]
• Official Symbol: COL5A3
• Synonyms: COL5A3; collagen, type V, alpha 3; collagen alpha-3(V) chain; pro-(alpha)3(V) collagen
• Gene ID: 50509
• mRNA Refseq: NM_015719
• Protein Refseq: NP_056534
• MIM: 120216
• UniProt ID: P25940