Recombinant Human COPS3 Protein, GST-tagged

• Cat.No.: COPS3-1702H
• Product Overview: Human COPS3 full-length ORF ( NP_003644.2, 1 a.a. - 423 a.a.) recombinant protein with GST-tag at N-terminal.

Specification

• Description: The protein encoded by this gene possesses kinase activity that phosphorylates regulators involved in signal transduction. It phosphorylates I kappa-Balpha, p105, and c-Jun. It acts as a docking site for complex-mediated phosphorylation. The gene is located within the Smith-Magenis syndrome region on chromosome 17. Several transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Oct 2015]
• Source: Wheat Germ
• Species: Human
• Tag: GST
• Molecular Mass: 74.3 kDa
• AA Sequence: MASALEQFVNSVRQLSAQGQMTQLC ELINKSGELLAKNLSHLDTVLGALD VQEHSLGVLAVLFVKFSMPSVPDFE TLFSQVQLFISTCNGEHIRYATDTF AGLCHQLTNALVERKQPLRGIGILK QAIDKMQMNTNQLTSIHADLCQLCL LAKCFKPALPYLDVDMMDICKENGA YDAKHFLCYYYYGGMIYTGLKNFER ALYFYEQAITTPAMAVSHIMLESYK KYILVSLILLGKVQQLPKYTSQIVG RFIKPLSNAYHELAQVYSTNNPSEL RNLVNKHSETFTRDNNMGLVKQCLS SLYKKNIQRLTKTFLTLSLQDMASR VQLSGPQEAEKYVLHMIEDGEIFAS INQKDGMVSFHDNPEKYNNPAMLHN IDQEMLKCIELDERLKAMDQEITVN PQFVQKSMGSQEDDSGNKPSSYS
• Applications: Enzyme-linked Immunoabsorbent Assay
  Western Blot (Recombinant protein)
  Antibody Production
  Protein Array
• Notes: Best use within three months from the date of receipt of this protein.
• Storage: Store at -80 centigrade. Aliquot to avoid repeated freezing and thawing.
• Storage Buffer: 50 mM Tris-HCI, 10 mM reduced Glutathione, pH=8.0 in the elution buffer.

Gene Information

• Gene Name: COPS3 COP9 constitutive photomorphogenic homolog subunit 3 (Arabidopsis) [ Homo sapiens ]
• Official Symbol: COPS3
• Synonyms: COPS3; COP9 constitutive photomorphogenic homolog subunit 3 (Arabidopsis); COP9 (constitutive photomorphogenic, Arabidopsis, homolog) subunit 3; COP9 signalosome complex subunit 3; CSN3; SGN3; signalosome subunit 3; COP9 complex subunit 3; JAB1-containing signalosome subunit 3
• Gene ID: 8533
• mRNA Refseq: NM_001199125
• Protein Refseq: NP_001186054
• MIM: 604665
• UniProt ID: Q9UNS2