Recombinant Human CPSF3L, GST-tagged

• Cat.No.: CPSF3L-11538H
• Product Overview: Recombinant Human CPSF3L protein, fused to GST-tag, was expressed in E.coli and purified by GSH-sepharose.

Specification

• Species: Human
• Source: E.coli
• Tag: GST
• Protein Length: C-term-356a.a.
• Description: The Integrator complex contains at least 12 subunits and associates with the C-terminal domain of RNA polymerase II large subunit (POLR2A; MIM 180660) and mediates the 3-prime end processing of small nuclear RNAs U1 (RNU1; MIM 180680) and U2 (RNU2; MIM 180690). INTS11, or CPSF3L, is the catalytic subunit of the Integrator complex (Baillat et al., 2005 [PubMed 16239144]).
• Storage: The protein is stored in PBS buffer at -20℃. Avoid repeated freezing and thawing cycles.
• Storage Buffer: 1M PBS (58mM Na2HPO4,17mM NaH2PO4, 68mM NaCl, pH8. ) added with 100mM GSH and 1% Triton X-100,15%glycerol.

Gene Information

• Gene Name: CPSF3L cleavage and polyadenylation specific factor 3-like [ Homo sapiens ]
• Official Symbol: CPSF3L
• Synonyms: CPSF3L; cleavage and polyadenylation specific factor 3-like; integrator complex subunit 11; CPSF73L; FLJ20542; INT11; INTS11; RC 68; CPSF3-like protein; related to CPSF subunits 68 kDa; protein related to CPSF subunits of 68 kDa; cleavage and polyadenylation-specific factor 3-like protein; RC68; RC-68; FLJ13294
• Gene ID: 54973
• mRNA Refseq: NM_001256456
• Protein Refseq: NP_001243385
• MIM: 611354
• UniProt ID: Q5TA45
• Chromosome Location: 1p36.33
• Function: hydrolase activity