Recombinant Human CRTAC1 Protein, GST-tagged

• Cat.No.: CRTAC1-1911H
• Product Overview: Human CRTAC1 full-length ORF ( AAH34245.1, 1 a.a. - 451 a.a.) recombinant protein with GST-tag at N-terminal.

Specification

• Description: This gene encodes a glycosylated extracellular matrix protein that is found in the interterritorial matrix of articular deep zone cartilage. This protein is used as a marker to distinguish chondrocytes from osteoblasts and mesenchymal stem cells in culture. The presence of FG-GAP motifs and an RGD integrin-binding motif suggests that this protein may be involved in cell-cell or cell-matrix interactions. Copy number alterations in this gene have been observed in neurofibromatosis type 1-associated glomus tumors. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Aug 2011]
• Source: Wheat Germ
• Species: Human
• Tag: GST
• Molecular Mass: 74.7 kDa
• AA Sequence: MDPEASDLSRGILALRDVAAEAGVS KYTGGRGVSVGPILSSSASDIFCDN ENGPNFLFHNRGDGTFVDAAASAGV DDPHQHGRGVALADFNRDGKVDIVY GNWNGPHRLYLQMSTHGKVRFRDIA SPKFSMPSPVRTVITADFDNDQELE IFFNNIAYRSSSANRLFRVIRREHG DPLIEELNPGDALEPEGRGTGGVVT DFDGDGMLDLILSHGESMAQPLSVF RGNQGFNNNWLRVVPRTRFGAFARG AKVVLYTKKSGAHLRIIDGGSGYLC EMEPVAHFGLGKDEASSVEVTWPDG KMVSRNVASGEMNSVLEILYPRDED TLQDPAPLECGQGFSQQENGHCMDT NECIQFPFVCPRDKPVCVNTYGSYR CRTNKKCSRGYEPNEDGTACVGTLG QSPGPRPTTPTAAAATAAAAAAAGA ATAAPVLVDGDLNLGSVVKESCEPS C
• Applications: Enzyme-linked Immunoabsorbent Assay
  Western Blot (Recombinant protein)
  Antibody Production
  Protein Array
• Notes: Best use within three months from the date of receipt of this protein.
• Storage: Store at -80 centigrade. Aliquot to avoid repeated freezing and thawing.
• Storage Buffer: 50 mM Tris-HCI, 10 mM reduced Glutathione, pH=8.0 in the elution buffer.

Gene Information

• Gene Name: CRTAC1 cartilage acidic protein 1 [ Homo sapiens ]
• Official Symbol: CRTAC1
• Synonyms: CRTAC1; cartilage acidic protein 1; ASPIC1; CEP 68; FLJ10320; acidic secreted protein in cartilage; chondrocyte expressed protein 68 kDa CEP-68; ASPIC; CEP-68
• Gene ID: 55118
• mRNA Refseq: NM_001206528
• Protein Refseq: NP_001193457
• MIM: 606276
• UniProt ID: Q9NQ79