Recombinant Human CSF3 protein, His/S-tagged
Cat.No. : | CSF3-180H |
Product Overview : | Recombinant Human CSF3 fused with His/S tag was expressed in E. coli. |
- Specification
- Gene Information
- Related Products
Description : | Granulocyte-colony stimulating factor (G-CSF) is a growth factor and an essential cytokine belonging to the CSF family of hormone-like glycoproteins that regulate haematopoietic cell proliferation and differentiation. G-CSF was isolated initially as a factor supporting the growth of colonies of granulocytes in soft agar cultures. Cells of the monocyte/macrophage lineage are among the most prominent sources of G-CSF, but this factor can also be produced by normal cells of mesodermal origin, including vascular endothelial cells, fibroblasts, and mesothelial cells. Production of G-CSF can be induced in vitro in these cells by a wide variety of stimulatory agents, including LPS, TNF, IL-1, IL-3, I L-4, and IFN-Gamma. G-CSF is likely to play a role in the basal regulation of neutrophil production, and also functions as a primary regulatory factor controlling the neutrophil response to inflammatory stimuli. Furthermore, G-CSF exhibits other biological activities besides the proliferative effects, since G-CSF appears to modulate the distribution of neutrophils and progenitor cells within the body. |
Source : | E. coli |
Species : | Human |
Tag : | His/S |
Form : | Lyophilized from sterile PBS, pH 7.4 |
Purity : | > 95 % as determined by SDS-PAGE |
Storage : | Store at -70 centigrade. Avoid repeated freeze/thaw cycles. |
Gene Name : | CSF3 colony stimulating factor 3 (granulocyte) [ Homo sapiens ] |
Official Symbol : | CSF3 |
Synonyms : | CSF3; colony stimulating factor 3 (granulocyte); C17orf33, chromosome 17 open reading frame 33 , G CSF, GCSF; granulocyte colony-stimulating factor; filgrastim; granulocyte colony stimulating factor; lenograstim; MGC45931; pluripoietin; GCSF; CSF3OS; C17orf33; |
Gene ID : | 1440 |
mRNA Refseq : | NM_000759 |
Protein Refseq : | NP_000750 |
MIM : | 138970 |
UniProt ID : | P09919 |
Chromosome Location : | 17q11.2-q12 |
Pathway : | Cytokine-cytokine receptor interaction, organism-specific biosystem; Cytokine-cytokine receptor interaction, conserved biosystem; Cytokines and Inflammatory Response, organism-specific biosystem; Hematopoietic cell lineage, organism-specific biosystem; Hematopoietic cell lineage, conserved biosystem; Jak-STAT signaling pathway, organism-specific biosystem; Jak-STAT signaling pathway, conserved biosystem; |
Function : | cytokine activity; cytokine activity; enzyme binding; granulocyte colony-stimulating factor receptor binding; growth factor activity; |
Products Types
◆ Recombinant Protein | ||
CSF3-281C | Active Recombinant Human CSF3 Protein | +Inquiry |
Csf3-047M | Active Recombinant Mouse Csf3 Protein | +Inquiry |
CSF3-396C | Active Recombinant Human CSF3 Protein | +Inquiry |
Csf3-20M | Active Recombinant Mouse Csf3 Protein (Glu55-Ala208), N-His tagged, Animal-free, Carrier-free | +Inquiry |
CSF3-341C | Active Recombinant Human CSF3 Protein | +Inquiry |
◆ Lysates | ||
CSF3-2948HCL | Recombinant Human CSF3 cell lysate | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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