| Description : |
The protein encoded by this gene is the receptor for colony stimulating factor 3, a cytokine that controls the production, differentiation, and function of granulocytes. The encoded protein, which is a member of the family of cytokine receptors, may also function in some cell surface adhesion or recognition processes. Alternatively spliced transcript variants have been described. Mutations in this gene are a cause of Kostmann syndrome, also known as severe congenital neutropenia. |
| Source : |
HEK293 |
| Species : |
Human |
| Tag : |
His |
| Form : |
Lyophilized |
| Molecular Mass : |
69 kDa |
| Protein Length : |
836 |
| AA Sequence : |
MARLGNCSLTWAALIILLLPGSLEE CGHISVSAPIVHLGDPITASCIIKQ NCSHLDPEPQILWRLGAELQPGGRQ QRLSDGTQESIITLPHLNHTQAFLS CCLNWGNSLQILDQVELRAGYPPAI PHNLSCLMNLTTSSLICQWEPGPET HLPTSFTLKSFKSRGNCQTQGDSIL DCVPKDGQSHCCIPRKHLLLYQNMG IWVQAENALGTSMSPQLCLDPMDVV KLEPPMLRTMDPSPEAAPPQAGCLQ LCWEPWQPGLHINQKCELRHKPQRG EASWALVGPLPLEALQYELCGLLPA TAYTLQIRCIRWPLPGHWSDWSPSL ELRTTERAPTVRLDTWWRQRQLDPR TVQLFWKPVPLEEDSGRIQGYVVSW RPSGQAGAILPLCNTTELSCTFHLP SEAQEVALVAYNSAGTSRPTPVVFS ESRGPALTRLHAMARDPHSLWVGWE PPNPWPQGYVIEWGLGPPSASNSNK TWRMEQNGRATGFLLKENIRPFQLY EIIVTPLYQDTMGPSQHVYAYSQEM APSHAPELHLKHIGKTWAQLEWVPE PPELGKSPLTHYTIFWTNAQNQSFS AILNASSRGFVLHGLEPASLYHIHL MAASQAGATNSTVLTLMTLTPEGSE LHIILGLFGLLLLLTCLCGTAWLCC SPNRKNPLWPSVPDPAHSSLGSWVP TIMEEDAFQLPGLGTPPITKLTVLE EDEKKPVPWESHNSSETCGLPTLVQ TYVLQGDPRAVSTQPQSQSGTSDQV LYGQLLGSPTSPGPGHYLRCDSTQP LLAGLTPSPKSYENLWFQASPLGTL VTPAPSQEDDCVFGPLLNFPLLQGI RVHGMEALGSF |
| Purity : |
> 98% |
| Applications : |
WB; ELISA; FACS; FC |
| Stability : |
This bioreagent is stable at 4 centigrade (short-term) and -70 centigrade(long-term). After reconstitution, sample may be stored at 4 centigrade for 2-7 days and below -18 centigrade for future use. |
| Storage : |
At -20 centigrade. |
| Concentration : |
1 mg/mL |
| Storage Buffer : |
PBS (pH 7.4-7.5). Sterile-filtered colorless solution. |
| Reconstitution : |
Reconstitute in sterile distilled H2O to no less than 100 μg/mL; dilute reconstituted stock further in other aqueous solutions if needed. Please review COA for lot-specific instructions. Final measurements should be determined by the end-user for optimal performance. |
