Recombinant Human CSK Protein (M1-L450), GST tagged
Cat.No. : | CSK-0765H |
Product Overview : | Recombinant Human GST-TEV-CSK(M1-L450 end) Protein was expressed in Insect cell. |
- Specification
- Gene Information
- Related Products
Description : | Non-receptor tyrosine-protein kinase that plays an important role in the regulation of cell growth, differentiation, migration and immune response. Phosphorylates tyrosine residues located in the C-terminal tails of Src-family kinases (SFKs) including LCK, SRC, HCK, FYN, LYN, CSK or YES1. Upon tail phosphorylation, Src-family members engage in intramolecular interactions between the phosphotyrosine tail and the SH2 domain that result in an inactive conformation. To inhibit SFKs, CSK is recruited to the plasma membrane via binding to transmembrane proteins or adapter proteins located near the plasma membrane. Suppresses signaling by various surface receptors, including T-cell receptor (TCR) and B-cell receptor (BCR) by phosphorylating and maintaining inactive several positive effectors such as FYN or LCK. |
Source : | Insect cell |
Species : | Human |
Tag : | GST |
Form : | Liquid |
Protein Length : | M1-L450 |
Endotoxin : | < 0.01 EU per μg of the protein |
Purity : | 90% |
Stability : | Samples are stable for up to twelve months from date of receipt at -20 to -80 centigrade. |
Storage : | Store it under sterile conditions at -20 to -80 centigrade. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles. |
Storage Buffer : | 50 mM Tris-HCl (pH7.5), 200 mM NaCl, 20% glycerol |
Shipping : | It is shipped out with blue ice. |
Gene Name : | CSK c-src tyrosine kinase [ Homo sapiens (human) ] |
Official Symbol : | CSK |
Synonyms : | CSK; c-src tyrosine kinase; tyrosine-protein kinase CSK; C-Src kinase; protein-tyrosine kinase CYL; MGC117393; |
Gene ID : | 1445 |
mRNA Refseq : | NM_001127190 |
Protein Refseq : | NP_001120662 |
MIM : | 124095 |
UniProt ID : | P41240 |
Products Types
◆ Recombinant Protein | ||
Csk-942M | Recombinant Mouse Csk Protein, MYC/DDK-tagged | +Inquiry |
CSK-0764H | Recombinant Human CSK Protein (M1-L450), Tag Free | +Inquiry |
CSK-3345H | Recombinant Human CSK Protein, MYC/DDK-tagged | +Inquiry |
CSK-342H | Active Recombinant Human CSK Protein, GST-tagged | +Inquiry |
CSK-882R | Recombinant Rhesus Macaque CSK Protein, His (Fc)-Avi-tagged | +Inquiry |
◆ Native Protein | ||
CSK-27872TH | Native Human CSK | +Inquiry |
◆ Lysates | ||
CSK-628HCL | Recombinant Human CSK cell lysate | +Inquiry |
CSK-001MCL | Recombinant Mouse CSK cell lysate | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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