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Recombinant Human CTBP1 Protein, GST-tagged

Cat.No. : CTBP1-2053H
Product Overview : Human CTBP1 full-length ORF ( AAH53320, 1 a.a. - 429 a.a.) recombinant protein with GST-tag at N-terminal.
  • Specification
  • Gene Information
  • Related Products
Description : This gene encodes a protein that binds to the C-terminus of adenovirus E1A proteins. This phosphoprotein is a transcriptional repressor and may play a role during cellular proliferation. This protein and the product of a second closely related gene, CTBP2, can dimerize. Both proteins can also interact with a polycomb group protein complex which participates in regulation of gene expression during development. Alternative splicing of transcripts from this gene results in multiple transcript variants. [provided by RefSeq, Jul 2008]
Source : Wheat Germ
Species : Human
Tag : GST
Molecular Mass : 72.93 kDa
AA Sequence : MSGVRPPIMNGPLHPRPLVALLDGR DCTVEMPILKDVATVAFCDAQSTQE IHEKVLNEAVGALMYHTITLTREDL EKFKALRIIVRIGSGFDNIDIKSAG DLGIAVCNVPAASVEETADSTLCHI LNLYRRATWLHQALREGTRVQSVEQ IREVASGAARIRGETLGIIGLGRVG QAVALRAKAFGFNVLFYDPYLSDGV ERALGLQRVSTLQDLLFHSDCVTLH CGLNEHNHHLINDFTVKQMRQGAFL VNTARGGLVDEKALAQALKEGRIRG AALDVHESEPFSFSQGPLKDAPNLI CTPHAAWYSEQASIEMREEAAREIR RAITGRIPDSLKNCVNKDHLTAATH WASMDPAVVHPELNGAAYRYPPGVV GVAPTGIPAAVEGIVPSAMSLSHGL PPVAHPPHAPSPGQTVKPEADRDHA SDQL
Applications : Enzyme-linked Immunoabsorbent Assay
Western Blot (Recombinant protein)
Antibody Production
Protein Array
Notes : Best use within three months from the date of receipt of this protein.
Storage : Store at -80 centigrade. Aliquot to avoid repeated freezing and thawing.
Storage Buffer : 50 mM Tris-HCI, 10 mM reduced Glutathione, pH=8.0 in the elution buffer.
Gene Name : CTBP1 C-terminal binding protein 1 [ Homo sapiens ]
Official Symbol : CTBP1
Synonyms : CTBP1; C-terminal binding protein 1; C-terminal-binding protein 1; BARS; brefeldin A ribosylated substrate; brefeldin A-ribosylated substrate; MGC104684;
Gene ID : 1487
mRNA Refseq : NM_001012614
Protein Refseq : NP_001012632
MIM : 602618
UniProt ID : Q13363

For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.

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Q&As (7)

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What is the primary role of CTBP1 in gene regulation? 02/19/2023

CTBP1 is a transcriptional co-repressor, regulating gene expression.

How do genetic variations in CTBP1 affect cellular differentiation? 09/15/2022

Genetic changes in CTBP1 affect cell development and differentiation.

How does CTBP1 interact with other transcriptional regulators? 02/11/2022

CTBP1 collaborates with transcription factors, influencing gene regulation.

What role does CTBP1 play in developmental processes? 10/07/2020

CTBP1 is involved in developmental processes and cell differentiation.

What potential therapeutic applications arise from targeting CTBP1 in diseases? 11/02/2019

Targeting CTBP1 could treat diseases with abnormal gene expression, including cancer.

How does CTBP1 contribute to transcriptional repression? 11/24/2018

It plays a key role in transcriptional repression, impacting gene activity.

What is the impact of altered CTBP1 activity on cancer progression? 04/08/2018

Altered CTBP1 activity is associated with cancer progression.

Customer Reviews (3)

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Reviews
10/12/2022

    Key to our research success, an integral research partner.

    02/15/2018

      Efficient and precise, a trusted research collaborator.

      04/03/2017

        Dependable partner, crucial for research integrity.

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