Recombinant Full Length Human CTBP1 Protein, C-Flag-tagged

• Cat.No.: CTBP1-448HFL
• Product Overview: Recombinant Full Length Human CTBP1 Protein, fused to Flag-tag at C-terminus, was expressed in Mammalian cells.

Specification

• Description: This gene encodes a protein that binds to the C-terminus of adenovirus E1A proteins. This phosphoprotein is a transcriptional repressor and may play a role during cellular proliferation. This protein and the product of a second closely related gene, CTBP2, can dimerize. Both proteins can also interact with a polycomb group protein complex which participates in regulation of gene expression during development. Alternative splicing of transcripts from this gene results in multiple transcript variants.
• Source: Mammalian cells
• Species: Human
• Tag: Flag
• Form: 25 mM Tris HCl, pH 7.3, 100 mM glycine, 10% glycerol.
• Molecular Mass: 47.4 kDa
• AA Sequence: MGSSHLLNKGLPLGVRPPIMNGPLH PRPLVALLDGRDCTVEMPILKDVAT VAFCDAQSTQEIHEKVLNEA VGALMYHTITLTREDLEKFKALRII VRIGSGFDNIDIKSAGDLGIAVCNV PAASVEETADSTLCHILNLY RRATWLHQALREGTRVQSVEQIREV ASGAARIRGETLGIIGLGRVGQAVA LRAKAFGFNVLFYDPYLSDG VERALGLQRVSTLQDLLFHSDCVTL HCGLNEHNHHLINDFTVKQMRQGAF LVNTARGGLVDEKALAQALK EGRIRGAALDVHESEPLSFSQGPLK DAPNLICTPHAAWYSEQASIEMREE AAREIRRAITGRIPDSLKNC VNKDHLTAATHWASMDPAVVHPELN GAAYRYPPGVVGVAPTGIPAAVEGI VPSAMSLSHGLPPVAHPPHA
  PSPGQTVKPEADRDHASDQLTRTRP LEQKLISEEDLAANDILDYKDDDDK V
• Purity: > 80% as determined by SDS-PAGE and Coomassie blue staining.
• Stability: Stable for 12 months from the date of receipt of the product under proper storage and handling conditions. Avoid repeated freeze-thaw cycles.
• Storage: Store at -80 centigrade.
• Concentration: >50 ug/mL as determined by microplate BCA method.
• Preparation: Recombinant protein was captured through anti-DDK affinity column followed by conventional chromatography steps.
• Protein Pathways: Chronic myeloid leukemia, Notch signaling pathway, Pathways in cancer, Wnt signaling pathway

Gene Information

• Gene Name: CTBP1 C-terminal binding protein 1 [ Homo sapiens (human) ]
• Official Symbol: CTBP1
• Synonyms: BARS; HADDTS
• Gene ID: 1487
• mRNA Refseq: NM_001328.3
• Protein Refseq: NP_001319.1
• MIM: 602618
• UniProt ID: Q13363