Recombinant Human CTNNB1 Protein, DDK-tagged
Cat.No. : | CTNNB1-3375H |
Product Overview : | Recombinant Human CTNNB1 protein, fused to DDK-tagged at C-terminus, was expressed in Insect cells. |
- Specification
- Gene Information
- Related Products
Description : | The protein encoded by this gene is part of a complex of proteins that constitute adherens junctions (AJs). AJs are necessary for the creation and maintenance of epithelial cell layers by regulating cell growth and adhesion between cells. The encoded protein also anchors the actin cytoskeleton and may be responsible for transmitting the contact inhibition signal that causes cells to stop dividing once the epithelial sheet is complete. Finally, this protein binds to the product of the APC gene, which is mutated in adenomatous polyposis of the colon. Mutations in this gene are a cause of colorectal cancer (CRC), pilomatrixoma (PTR), medulloblastoma (MDB), and ovarian cancer. Alternative splicing results in multiple transcript variants. |
Source : | Insect cells |
Species : | Human |
Tag : | DDK |
Form : | 50 mM Tris-HCl, pH 8.0, 100 mM glycine, 10% glycerol. Store at -80 Centigrade. Avoid repeated freeze-thaw cycles. Stable for at least 3 months from receipt of products under proper storage and handling conditions. |
Molecular Mass : | 85 kDa |
Purity : | > 80% as determined by SDS-PAGE and Coomassie blue staining |
Concentration : | >50 ug/mL as determined by microplate BCA method |
Publication : |
A Novel Anti-Cancer Agent, 1-(3,5-Dimethoxyphenyl)-4-[(6-Fluoro-2-Methoxyquinoxalin-3-yl)Aminocarbonyl] Piperazine (RX-5902), Interferes With β-Catenin Function Through Y593 Phospho-p68 RNA Helicase (2015)
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Gene Name : | CTNNB1 catenin (cadherin-associated protein), beta 1, 88kDa [ Homo sapiens ] |
Official Symbol : | CTNNB1 |
Synonyms : | armadillo; CTNNB; MRD19 |
Gene ID : | 1499 |
mRNA Refseq : | NM_001098209 |
Protein Refseq : | NP_001091679 |
MIM : | 116806 |
UniProt ID : | P35222 |
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Ctnnb1-779M | Recombinant Mouse Ctnnb1 Protein, MYC/DDK-tagged | +Inquiry |
◆ Lysates | ||
CTNNB1-001MCL | Recombinant Mouse CTNNB1 cell lysate | +Inquiry |
CTNNB1-563HCL | Recombinant Human CTNNB1 cell lysate | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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