Recombinant Human CTSC Protein, GST-tagged
Cat.No. : | CTSC-2102H |
Product Overview : | Human CTSC full-length ORF ( NP_001805.1, 1 a.a. - 463 a.a.) recombinant protein with GST-tag at N-terminal. |
- Specification
- Gene Information
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Description : | This gene encodes a member of the peptidase C1 family and lysosomal cysteine proteinase that appears to be a central coordinator for activation of many serine proteinases in cells of the immune system. Alternative splicing results in multiple transcript variants, at least one of which encodes a preproprotein that is proteolytically processed to generate heavy and light chains that form a disulfide-linked dimer. A portion of the propeptide acts as an intramolecular chaperone for the folding and stabilization of the mature enzyme. This enzyme requires chloride ions for activity and can degrade glucagon. Defects in the encoded protein have been shown to be a cause of Papillon-Lefevre syndrome, an autosomal recessive disorder characterized by palmoplantar keratosis and periodontitis. [provided by RefSeq, Nov 2015] |
Source : | Wheat Germ |
Species : | Human |
Tag : | GST |
Molecular Mass : | 78.2 kDa |
AA Sequence : | MGAGPSLLLAALLLLLSGDGAVRCD TPANCTYLDLLGTWVFQVGSSGSQR DVNCSVMGPQEKKVVVYLQKLDTAY DDLGNSGHFTIIYNQGFEIVLNDYK WFAFFKYKEEGSKVTTYCNETMTGW VHDVLGRNWACFTGKKVGTASENVY VNTAHLKNSQEKYSNRLYKYDHNFV KAINAIQKSWTATTYMEYETLTLGD MIRRSGGHSRKIPRPKPAPLTAEIQ QKILHLPTSWDWRNVHGINFVSPVR NQASCGSCYSFASMGMLEARIRILT NNSQTPILSPQEVVSCSQYAQGCEG GFPYLIAGKYAQDFGLVEEACFPYT GTDSPCKMKEDCFRYYSSEYHYVGG FYGGCNEALMKLELVHHGPMAVAFE VYDDFLHYKKGIYHHTGLRDPFNPF ELTNHAVLLVGYGTDSASGMDYWIV KNSWGTGWGENGYFRIRRGTDECAI ESIAVAATPIPKL |
Applications : | Enzyme-linked Immunoabsorbent Assay Western Blot (Recombinant protein) Antibody Production Protein Array |
Notes : | Best use within three months from the date of receipt of this protein. |
Storage : | Store at -80 centigrade. Aliquot to avoid repeated freezing and thawing. |
Storage Buffer : | 50 mM Tris-HCI, 10 mM reduced Glutathione, pH=8.0 in the elution buffer. |
Gene Name : | CTSC cathepsin C [ Homo sapiens ] |
Official Symbol : | CTSC |
Synonyms : | CTSC; cathepsin C; PALS, PLS; dipeptidyl peptidase 1; DPP1; cathepsin J; dipeptidyl peptidase I; dipeptidyl transferase; dipeptidyl-peptidase I; JP; HMS; JPD; PLS; CPPI; DPPI; PALS; DPP-I; |
Gene ID : | 1075 |
mRNA Refseq : | NM_001114173 |
Protein Refseq : | NP_001107645 |
MIM : | 602365 |
UniProt ID : | P53634 |
Products Types
◆ Recombinant Protein | ||
Ctsc-001M | Active Recombinant Mouse Ctsc Protein, His-tagged | +Inquiry |
Ctsc-2368M | Recombinant Mouse Ctsc Protein, Myc/DDK-tagged | +Inquiry |
CTSC-176C | Recombinant Cynomolgus Monkey CTSC Protein, His (Fc)-Avi-tagged | +Inquiry |
CTSC-3367H | Recombinant Human CTSC Protein, MYC/DDK-tagged | +Inquiry |
CTSC-686H | Recombinant Human CTSC Protein, His (Fc)-Avi-tagged | +Inquiry |
◆ Lysates | ||
CTSC-3024HCL | Recombinant Human CTSC cell lysate | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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