Recombinant Human CUL5 Protein (A2-A780), Tag Free
Cat.No. : | CUL5-0331H |
Product Overview : | Recombinant Human (GG)-CUL5(A2-A780 end) Protein was expressed in Insect cell. |
- Specification
- Gene Information
- Related Products
Description : | Core component of multiple SCF-like ECS (Elongin-Cullin 2/5-SOCS-box protein) E3 ubiquitin-protein ligase complexes, which mediate the ubiquitination and subsequent proteasomal degradation of target proteins. As a scaffold protein may contribute to catalysis through positioning of the substrate and the ubiquitin-conjugating enzyme. The functional specificity of the E3 ubiquitin-protein ligase complex depends on the variable substrate recognition component. ECS(SOCS1) seems to direct ubiquitination of JAK2. ECS(KLHDC1) complex is part of the DesCEND (destruction via C-end degrons) pathway and mediates ubiquitination and degradation of truncated SELENOS selenoprotein produced by failed UGA/Sec decoding, which ends with a glycine. May form a cell surface vasopressin receptor. |
Source : | Insect cell |
Species : | Human |
Tag : | No tag |
Form : | Liquid |
Protein Length : | A2-A780 |
Endotoxin : | < 0.01 EU per μg of the protein |
Purity : | 90% |
Stability : | Samples are stable for up to twelve months from date of receipt at -20 to -80 centigrade. |
Storage : | Store it under sterile conditions at -20 to -80 centigrade. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles. |
Storage Buffer : | 50 mM Tris-HCl (pH7.5), 200 mM NaCl, 20% glycerol |
Shipping : | It is shipped out with blue ice. |
Gene Name : | CUL5 cullin 5 [ Homo sapiens (human) ] |
Official Symbol : | CUL5 |
Synonyms : | CUL5; cullin 5; cullin-5; VACM 1; CUL-5; Vasopressin-activated calcium-mobilizing receptor-1; vasopressin-activated calcium-mobilizing receptor 1; Cullin-5 (vasopressin-activated calcium-mobilizing receptor-1); VACM1; VACM-1; |
Gene ID : | 8065 |
mRNA Refseq : | NM_003478 |
Protein Refseq : | NP_003469 |
MIM : | 601741 |
UniProt ID : | Q93034 |
Products Types
◆ Recombinant Protein | ||
CUL5-2136H | Recombinant Human CUL5 Protein, GST-tagged | +Inquiry |
CUL5-1337R | Recombinant Rat CUL5 Protein, His (Fc)-Avi-tagged | +Inquiry |
Cul5-2379M | Recombinant Mouse Cul5 Protein, Myc/DDK-tagged | +Inquiry |
CUL5-0332H | Recombinant Human CUL5 Protein (A2-A780), His/Strep tagged | +Inquiry |
CUL5-02H | Active Recombinant Human CUL5/RBX2 Complex Protein, His-Tagged | +Inquiry |
◆ Lysates | ||
CUL5-7180HCL | Recombinant Human CUL5 293 Cell Lysate | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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