Recombinant Human CX3CL1 Protein, Biotinylated

• Cat.No.: CX3CL1-481H
• Product Overview: Biotinylated Recombinant human CX3CL1 protein

Specification

• Description: This gene belongs to the CX3C subgroup of chemokines, characterized by the number of amino acids located between the conserved cysteine residues. This is the only member of the CX3C subgroup, which contains three amino acids between cysteine residues, resulting in a Cys-X-X-X-Cys configuration. The encoded protein contains an extended mucin-like stalk with a chemokine domain on top, and exists in both a membrane-anchored form where it acts as a binding molecule, or, in soluble form, as a chemotactic cytokine. The mature form of this protein can be cleaved at the cell surface, yielding different soluble forms that can interact with the G-protein coupled receptor, C-X3-C motif chemokine receptor 1 gene product. This gene plays a role in a wide range of diseases, including cancer, vasculitis, neuropathies, atherosclerosis, inflammatory diseases, and in human immunodeficiency virus infections.
• Species: Human
• Form: Lyophilized
• Protein Length: 397
• AA Sequence: MAPISLSWLLRLATFCHLTVLLAGQ HHGVTKCNITCSKMTSKIPVALLIH YQQNQASCGKRAIILETRQHRLFCA DPKEQWVKDAMQHLDRQAAALTRNG GTFEKQIGEVKPRTTPAAGGMDESV VLEPEATGESSSLEPTPSSQEAQRA LGTSPELPTGVTGSSGTRLPPTPKA QDGGPVGTELFRVPPVSTAATWQSS APHQPGPSLWAEAKTSEAPSTQDPS TQASTASSPAPEENAPSEGQRVWGQ GQSPRPENSLEREEMGPVPAHTDAF QDWGPGSMAHVSVVPVSSEGTPSRE PVASGSWTPKAEEPIHATMDPQRLG VLITPVPDAQAATRRQAVGLLAFLG LLFCLGVAMFTYQSLQGCPRKMAGE MAEGLRYIPRSCGSNSYVLVPV
• Purity: > 98%
• Applications: WB; ELISA; FACS; FC
• Stability: This bioreagent is stable at 4 centigrade (short-term) and -70 centigrade(long-term). After reconstitution, sample may be stored at 4 centigrade for 2-7 days and below -18 centigrade for future use.
• Storage: At -20 centigrade.
• Storage Buffer: PBS (pH 7.4-7.5). Sterile-filtered colorless solution.
• Reconstitution: Reconstitute in sterile distilled H2O to no less than 100 μg/mL; dilute reconstituted stock further in other aqueous solutions if needed. Please review COA for lot-specific instructions. Final measurements should be determined by the end-user for optimal performance.

Gene Information

• Gene Name: CX3CL1 chemokine (C-X3-C motif) ligand 1 [ Homo sapiens (human) ]
• Official Symbol: CX3CL1
• Synonyms: CX3CL1; chemokine (C-X3-C motif) ligand 1; SCYD1, small inducible cytokine subfamily D (Cys X3 Cys), member 1 (fractalkine, neurotactin); fractalkine; ABCD 3; C3Xkine; CXC3; CXC3C; neurotactin; NTN; C-X3-C motif chemokine 1; small-inducible cytokine D1; CX3C membrane-anchored chemokine; small inducible cytokine subfamily D (Cys-X3-Cys), member-1; small inducible cytokine subfamily D (Cys-X3-Cys), member 1 (fractalkine, neurotactin); NTT; SCYD1; ABCD-3
• Gene ID: 6376
• mRNA Refseq: NM_002996
• Protein Refseq: NP_002987
• MIM: 601880
• UniProt ID: P78423