Creative BioMart to Present at
                        BIO-Europe Spring Creative BioMart to Present at AACR Annual Meeting|Apr. 5-10, 2024|Booth #2953

Recombinant Human CXCL12 Protein, DYKDDDDK-tagged

Cat.No. : CXCL12-191H
Product Overview : Recombinant Human C-X-C motif chemokine ligand 12(CXCL12), transcript variant 1(NM_199168), with a DYKDDDDK tag, was expressed in human cells.
  • Specification
  • Gene Information
  • Related Products
Description : This antimicrobial gene encodes a stromal cell-derived alpha chemokine member of the intercrine family. The encoded protein functions as the ligand for the G-protein coupled receptor, chemokine (C-X-C motif) receptor 4, and plays a role in many diverse cellular functions, including embryogenesis, immune surveillance, inflammation response, tissue homeostasis, and tumor growth and metastasis. Mutations in this gene are associated with resistance to human immunodeficiency virus type 1 infections. Multiple transcript variants encoding different isoforms have been found for this gene.
Source : Human Cells
Species : Human
Tag : DYKDDDDK
Form : Purified protein formulated in a sterile solution of TBS buffer, pH7.70, without any preservatives.
Molecular Mass : 8.0 kDa
Endotoxin : Endotoxin level is < 0.1 ng/µg of protein (<1EU /µg)
Purity : >90% by SDS-PAGE gel and Coomassie Blue staining
Applications : Antigens, Western, ELISA and other in vitro binding or in vivo functional assays, and protein-protein interaction studies.
Gene Name : CXCL12 chemokine (C-X-C motif) ligand 12 [ Homo sapiens ]
Official Symbol : CXCL12
Synonyms : CXCL12; chemokine (C-X-C motif) ligand 12; SDF1, SDF1A, SDF1B, stromal cell derived factor 1; stromal cell-derived factor 1; PBSF; SCYB12; SDF 1a; SDF 1b; TLSF a; TLSF b; TPAR1; intercrine reduced in hepatomas; pre-B cell growth-stimulating factor; IRH; SDF1; TLSF; SDF1A; SDF1B;
Gene ID : 6387
mRNA Refseq : NM_000609
Protein Refseq : NP_000600
MIM : 600835
UniProt ID : P48061

For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.

Inquiry

  • Q&As
  • Reviews

Q&As (5)

Ask a question
How are researchers using CXCL12 in neurodegenerative disease research? 08/27/2022

CXCL12 is being investigated for its role in neuroprotection and neuroregeneration in conditions like Alzheimer's and Parkinson's disease.

Are there diagnostic tests that measure CXCL12 levels in patients? 12/19/2021

Yes, ELISA and other assays can be used to measure CXCL12 levels, aiding in the diagnosis and monitoring of certain diseases.

Can CXCL12 be used as a biomarker for specific diseases? 02/03/2021

CXCL12 levels can serve as a biomarker for various diseases, such as HIV, cancer, and inflammatory disorders.

How is CXCL12 being researched for cardiovascular therapies? 06/16/2019

Scientists are exploring the potential of CXCL12-based therapies to promote vascular repair and treat heart diseases.

Can CXCL12-based therapies help in spinal cord injury treatment? 04/02/2019

Researchers are studying CXCL12-based treatments to promote nerve regeneration and functional recovery after spinal cord injuries.

Customer Reviews (3)

Write a review
Reviews
06/15/2022

    The CXCL12 protein is of exceptional quality, making it an ideal candidate to fulfill my experimental requirements.

    01/08/2022

      The manufacturer's commitment to providing excellent technical support is truly commendable, as they have proven to be readily available to assist in resolving any concerns or challenges I encountered while working with the protein.

      04/26/2021

        Its purity and integrity have consistently delivered reliable and robust results in my research.

        Ask a Question for All CXCL12 Products

        Required fields are marked with *

        My Review for All CXCL12 Products

        Required fields are marked with *

        0

        Inquiry Basket

        cartIcon
        logo

        FOLLOW US

        Terms and Conditions        Privacy Policy

        Copyright © 2024 Creative BioMart. All Rights Reserved.

        Contact Us

        • /

        Stay Updated on the Latest Bioscience Trends