Recombinant Human CYLD Protein, His-tagged
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| Cat.No. : | CYLD-23H |
| Product Overview : | Recombinant human CYLD isoform 1 protein Protein contains an N-terminal 6-His tag was expressed in Spodoptera frugiperda, Sf 21. |
| Description : | This gene is encodes a cytoplasmic protein with three cytoskeletal-associated protein-glycine-conserved (CAP-GLY) domains that functions as a deubiquitinating enzyme. Mutations in this gene have been associated with cylindromatosis, multiple familial trichoepithelioma, and Brooke-Spiegler syndrome. Alternate transcriptional splice variants, encoding different isoforms, have been characterized. |
| Source : | Insect Cell |
| Species : | Human |
| Tag : | His |
| Bio-activity : | Recombinant Human His6-CYLD Isoform 1 is a Ubiquitin-specific deconjugating enzyme. Reaction conditions will need to be optimized for each specific application. We recommend an initial Recombinant Human His6-CYLD Isoform 1 concentration of 50-500 nM. |
| Molecular Mass : | 108 kDa |
| Purity : | >90%, by SDS-PAGE under reducing conditions and visualized by Colloidal Coomassie® Blue stain. |
| Storage : | Avoid repeated freeze-thaw cycles. 12 months from date of receipt, -70 centigrade as supplied. 3 months, -70 centigrade under sterile conditions after opening. |
| Storage Buffer : | X mg/ml (X μM) in 50 mM HEPES pH 8.0, 200 mM NaCl, 2 mM DTT |
| Shipping : | The product is shipped with dry ice or equivalent. |
| Gene Name : | CYLD CYLD lysine 63 deubiquitinase [ Homo sapiens (human) ] |
| Official Symbol : | CYLD |
| Synonyms : | CYLD; CYLD lysine 63 deubiquitinase; EAC; MFT; SBS; TEM; BRSS; CDMT; MFT1; CYLD1; CYLDI; USPL2; ubiquitin carboxyl-terminal hydrolase CYLD; cylindromatosis (turban tumor syndrome); deubiquitinating enzyme CYLD; probable ubiquitin carboxyl-terminal hydrolase CYLD; ubiquitin specific peptidase like 2; ubiquitin thioesterase CYLD; ubiquitin thiolesterase CYLD; ubiquitin-specific-processing protease CYLD; EC 3.4.19.12 |
| Gene ID : | 1540 |
| mRNA Refseq : | NM_015247 |
| Protein Refseq : | NP_056062 |
| MIM : | 605018 |
| UniProt ID : | Q9NQC7 |
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