Recombinant Human CYLD Protein, His-tagged

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Recombinant Human CYLD Protein, His-tagged

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Cat.No. : CYLD-23H
Product Overview : Recombinant human CYLD isoform 1 protein Protein contains an N-terminal 6-His tag was expressed in Spodoptera frugiperda, Sf 21.
Description : This gene is encodes a cytoplasmic protein with three cytoskeletal-associated protein-glycine-conserved (CAP-GLY) domains that functions as a deubiquitinating enzyme. Mutations in this gene have been associated with cylindromatosis, multiple familial trichoepithelioma, and Brooke-Spiegler syndrome. Alternate transcriptional splice variants, encoding different isoforms, have been characterized.
Source : Insect Cell
Species : Human
Tag : His
Bio-activity : Recombinant Human His6-CYLD Isoform 1 is a Ubiquitin-specific deconjugating enzyme. Reaction conditions will need to be optimized for each specific application. We recommend an initial Recombinant Human His6-CYLD Isoform 1 concentration of 50-500 nM.
Molecular Mass : 108 kDa
Purity : >90%, by SDS-PAGE under reducing conditions and visualized by Colloidal Coomassie® Blue stain.
Storage : Avoid repeated freeze-thaw cycles.
12 months from date of receipt, -70 centigrade as supplied. 3 months, -70 centigrade under sterile conditions after opening.
Storage Buffer : X mg/ml (X μM) in 50 mM HEPES pH 8.0, 200 mM NaCl, 2 mM DTT
Shipping : The product is shipped with dry ice or equivalent.
Gene Name : CYLD CYLD lysine 63 deubiquitinase [ Homo sapiens (human) ]
Official Symbol : CYLD
Synonyms : CYLD; CYLD lysine 63 deubiquitinase; EAC; MFT; SBS; TEM; BRSS; CDMT; MFT1; CYLD1; CYLDI; USPL2; ubiquitin carboxyl-terminal hydrolase CYLD; cylindromatosis (turban tumor syndrome); deubiquitinating enzyme CYLD; probable ubiquitin carboxyl-terminal hydrolase CYLD; ubiquitin specific peptidase like 2; ubiquitin thioesterase CYLD; ubiquitin thiolesterase CYLD; ubiquitin-specific-processing protease CYLD; EC 3.4.19.12
Gene ID : 1540
mRNA Refseq : NM_015247
Protein Refseq : NP_056062
MIM : 605018
UniProt ID : Q9NQC7
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.

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