Active Recombinant Human CYLD Protein, His-tagged
Cat.No. : | CYLD-23H |
Product Overview : | Recombinant human CYLD isoform 1 protein Protein contains an N-terminal 6-His tag was expressed in Spodoptera frugiperda, Sf 21. |
- Specification
- Gene Information
- Related Products
Description : | This gene is encodes a cytoplasmic protein with three cytoskeletal-associated protein-glycine-conserved (CAP-GLY) domains that functions as a deubiquitinating enzyme. Mutations in this gene have been associated with cylindromatosis, multiple familial trichoepithelioma, and Brooke-Spiegler syndrome. Alternate transcriptional splice variants, encoding different isoforms, have been characterized. |
Source : | Insect Cell |
Species : | Human |
Tag : | His |
Bio-activity : | Recombinant Human His6-CYLD Isoform 1 is a Ubiquitin-specific deconjugating enzyme. Reaction conditions will need to be optimized for each specific application. We recommend an initial Recombinant Human His6-CYLD Isoform 1 concentration of 50-500 nM. |
Molecular Mass : | 108 kDa |
Purity : | >90%, by SDS-PAGE under reducing conditions and visualized by Colloidal Coomassie® Blue stain. |
Storage : | Avoid repeated freeze-thaw cycles. 12 months from date of receipt, -70 centigrade as supplied. 3 months, -70 centigrade under sterile conditions after opening. |
Storage Buffer : | X mg/ml (X μM) in 50 mM HEPES pH 8.0, 200 mM NaCl, 2 mM DTT |
Shipping : | The product is shipped with dry ice or equivalent. |
Gene Name : | CYLD CYLD lysine 63 deubiquitinase [ Homo sapiens (human) ] |
Official Symbol : | CYLD |
Synonyms : | CYLD; CYLD lysine 63 deubiquitinase; EAC; MFT; SBS; TEM; BRSS; CDMT; MFT1; CYLD1; CYLDI; USPL2; ubiquitin carboxyl-terminal hydrolase CYLD; cylindromatosis (turban tumor syndrome); deubiquitinating enzyme CYLD; probable ubiquitin carboxyl-terminal hydrolase CYLD; ubiquitin specific peptidase like 2; ubiquitin thioesterase CYLD; ubiquitin thiolesterase CYLD; ubiquitin-specific-processing protease CYLD; EC 3.4.19.12 |
Gene ID : | 1540 |
mRNA Refseq : | NM_015247 |
Protein Refseq : | NP_056062 |
MIM : | 605018 |
UniProt ID : | Q9NQC7 |
Products Types
◆ Recombinant Protein | ||
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For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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