Recombinant Human CYP2B6 Protein


Home / Products / Recombinant Proteins / Recombinant Human CYP2B6 Protein

Recombinant Human CYP2B6 Protein

CYP2B6 Related Products

Price Inquiry

Welcome! For price inquiries, please feel free to contact us through the form below. We will get back to you as soon as possible.

Cat.No. : CYP2B6-73H
Product Overview : Recombinant human CYP2B6 protein and CYP-reductase without tag were coexpressed in E. coli.
Description : This gene, CYP2B6, encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. This protein localizes to the endoplasmic reticulum and its expression is induced by phenobarbital. The enzyme is known to metabolize some xenobiotics, such as the anti-cancer drugs cyclophosphamide and ifosphamide. Transcript variants for this gene have been described; however, it has not been resolved whether these transcripts are in fact produced by this gene or by a closely related pseudogene, CYP2B7. Both the gene and the pseudogene are located in the middle of a CYP2A pseudogene found in a large cluster of cytochrome P450 genes from the CYP2A, CYP2B and CYP2F subfamilies on chromosome 19q.
Source : E. coli
Species : Human
Bio-activity : Cytochrome c Reductase Activity: 257 nmol/min/mg protein
P450 Activity Data(Unless otherwise stated, all assays are carried out at 37 centigrade in 100 mM potassium phosphate buffer (pH 7.4) containing 5mM magnesium chloride and an NADPH generating system [5 mM glucose 6-phosphate, 1 mM NADP+, 1 U/ml glucose 6-phosphate dehydrogenase])
Activity: Diazepam N-demethylase
Linear with time up to: 10 min(Determined at 100 μM substrate, using a P450 concentration of 50 pmol/ml)
Linear with P450 up to: 100 pmol/ml(Determined at 100 μM substrate, using an incubation time of 5 min)
Vmax: 0.72 pmol/min/pmol CYP
Km: 133 μM
Usage : For laboratory (research) purposes only
Storage : Store at -80 centigrade. Avoid frequent temperature changes. Thaw on ice.
Concentration : P450 Concentration: 6.1 nmol/ml
Protein Concentration: 18.3 mg/ml
Specific P450 Content: 333 pmol/mg protein
Storage Buffer : 50 mM Tris-acetate (pH 7.6), 250 mM sucrose, 0.25 mM EDTA
Gene Name : CYP2B6 cytochrome P450 family 2 subfamily B member 6 [ Homo sapiens (human) ]
Official Symbol : CYP2B6
Synonyms : CYP2B6; cytochrome P450 family 2 subfamily B member 6; CPB6; EFVM; IIB1; P450; CYP2B; CYP2B7; CYP2B7P; CYPIIB6; cytochrome P450 2B6; 1,4-cineole 2-exo-monooxygenase; cytochrome P450 IIB1; cytochrome P450, family 2, subfamily B, polypeptide 6; cytochrome P450, subfamily IIB (phenobarbital-inducible), polypeptide 6
Gene ID : 1555
mRNA Refseq : NM_000767
Protein Refseq : NP_000758
MIM : 123930
UniProt ID : P20813

Products Types

◆ Recombinant Protein

CYP2B6-113DRecombinant Dog CYP2B6 Protein+Inquiry
CYP2B6-22HRecombinant Human CYP2B6 Protein+Inquiry
CYP2B6-21HRecombinant Human CYP2B6 Protein+Inquiry
CYP2B6-231HRecombinant Human CYP2B6+Inquiry
CYP2B6-192HRecombinant Human CYP2B6+Inquiry

See All CYP2B6 Recombinant Protein

◆ Assay kits

Kit-1943CYP2B6 Induction Reporter Assay Kit+Inquiry

See All CYP2B6 Assay kits

Related Gene


Online Inquiry

  • Note: There will be extra charge for optional service!
  • Verification Code Please review Creative BioMart's privacy policy for more information

Optional Service: Optional requirements on this protein

Other Requirements:

Apply For A Coupon

$50 OFF Your First Purchase

Apply For a Coupon

Enter your email here to subscribe.

creative biomart inc.

Easy access to products and services you need from our library via powerful searching tools.

Follow Us

Copyright © 2007 – 2021 Creative BioMart. All Rights Reserved. Terms and Conditions | Privacy Policy