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Recombinant Human CYP3A5 Protein, Myc/DDK-tagged, C13 and N15-labeled

Cat.No. : CYP3A5-3567H
Product Overview : CYP3A5 MS Standard C13 and N15-labeled recombinant protein (NP_000768) with a C-terminal MYC/DDK tag, was expressed in HEK293 cells.
  • Specification
  • Gene Information
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Description : This gene encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. The encoded protein metabolizes drugs as well as the steroid hormones testosterone and progesterone. This gene is part of a cluster of cytochrome P450 genes on chromosome 7q21.1. Two pseudogenes of this gene have been identified within this cluster on chromosome 7. Expression of this gene is widely variable among populations, and a single nucleotide polymorphism that affects transcript splicing has been associated with susceptibility to hypertensions. Alternative splicing results in multiple transcript variants.
Source : HEK293
Species : Human
Tag : Myc/DDK
Molecular Mass : 57.1 kDa
AA Sequence : MDLIPNLAVETWLLLAVSLVLLYLY GTRTHGLFKRLGIPGPTPLPLLGNV LSYRQGLWKFDTECYKKYGKMWGTY EGQLPVLAITDPDVIRTVLVKECYS VFTNRRSLGPVGFMKSAISLAEDEE WKRIRSLLSPTFTSGKLKEMFPIIA QYGDVLVRNLRREAEKGKPVTLKDI FGAYSMDVITGTSFGVNIDSLNNPQ DPFVESTKKFLKFGFLDPLFLSIIL FPFLTPVFEALNVSLFPKDTINFLS KSVNRMKKSRLNDKQKHRLDFLQLM IDSQNSKETESHKALSDLELAAQSI IFIFAGYETTSSVLSFTLYELATHP DVQQKLQKEIDAVLPNKAPPTYDAV VQMEYLDMVVNETLRLFPVAIRLER TCKKDVEINGVFIPKGSMVVIPTYA LHHDPKYWTEPEEFRPERFSKKKDS IDPYIYTPFGTGPRNCIGMRFALMN MKLALIRVLQNFSFKPCKETQIPLK LDTQGLLQPEKPIVLKVDSRDGTLS GETRTRPLEQKLISEEDLAANDILD YKDDDDKV
Purity : > 80% as determined by SDS-PAGE and Coomassie blue staining
Stability : Stable for 3 months from receipt of products under proper storage and handling conditions.
Storage : Store at -80 centigrade. Avoid repeated freeze-thaw cycles.
Concentration : 50 μg/mL as determined by BCA
Storage Buffer : 100 mM glycine, 25 mM Tris-HCl, pH 7.3.
Gene Name : CYP3A5 cytochrome P450 family 3 subfamily A member 5 [ Homo sapiens (human) ]
Official Symbol : CYP3A5
Synonyms : CYP3A5; cytochrome P450, family 3, subfamily A, polypeptide 5; cytochrome P450, subfamily IIIA (niphedipine oxidase), polypeptide 5; cytochrome P450 3A5; CP35; P450PCN3; PCN3; cytochrome P-450; niphedipine oxidase; cytochrome P450 HLp2; cytochrome P450-PCN3; microsomal monooxygenase; xenobiotic monooxygenase; aryl hydrocarbon hydroxylase; flavoprotein-linked monooxygenase; CYPIIIA5; FLJ31317; DKFZp686L16231;
Gene ID : 1577
mRNA Refseq : NM_000777
Protein Refseq : NP_000768
MIM : 605325
UniProt ID : P20815

For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.

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