Recombinant Human CYP3A7 Protein, GST-tagged

• Cat.No.: CYP3A7-2277H
• Product Overview: Human CYP3A7 full-length ORF ( NP_000756.1, 1 a.a. - 503 a.a.) recombinant protein with GST-tag at N-terminal.

Specification

• Description: This gene encodes a member of the cytochrome P450 superfamily of enzymes, which participate in drug metabolism and the synthesis of cholesterol, steroids and other lipids. This enzyme hydroxylates testosterone and dehydroepiandrosterone 3-sulphate, which is involved in the formation of estriol during pregnancy. This gene is part of a cluster of related genes on chromosome 7q21.1. Naturally-occurring readthrough transcription occurs between this gene and the downstream CYP3A51P pseudogene and is represented by GeneID:100861540. [provided by RefSeq, Jan 2015]
• Source: Wheat Germ
• Species: Human
• Tag: GST
• Molecular Mass: 83.9 kDa
• AA Sequence: MDLIPNLAVETWLLLAVSLILLYLY GTRTHGLFKKLGIPGPTPLPFLGNA LSFRKGYWTFDMECYKKYRKVWGIY DCQQPMLAITDPDMIKTVLVKECYS VFTNRRPFGPVGFMKNAISIAEDEE WKRIRSLLSPTFTSGKLKEMVPIIA QYGDVLVRNLRREAETGKPVTLKHV FGAYSMDVITSTSFGVSIDSLNNPQ DPFVENTKKLLRFNPLDPFVLSIKV FPFLTPILEALNITVFPRKVISFLT KSVKQIKEGRLKETQKHRVDFLQLM IDSQNSKDSETHKALSDLELMAQSI IFIFAGYETTSSVLSFIIYELATHP DVQQKVQKEIDTVLPNKAPPTYDTV LQLEYLDMVVNETLRLFPVAMRLER VCKKDVEINGMFIPKGVVVMIPSYV LHHDPKYWTEPEKFLPERFSKKNKD NIDPYIYTPFGSGPRNCIGMRFALV NMKLALVRVLQNFSFKPCKETQIPL KLRFGGLLLTEKPIVLKAESRDETV SGA
• Applications: Enzyme-linked Immunoabsorbent Assay
  Western Blot (Recombinant protein)
  Antibody Production
  Protein Array
• Notes: Best use within three months from the date of receipt of this protein.
• Storage: Store at -80 centigrade. Aliquot to avoid repeated freezing and thawing.
• Storage Buffer: 50 mM Tris-HCI, 10 mM reduced Glutathione, pH=8.0 in the elution buffer.

Gene Information

• Gene Name: CYP3A7 cytochrome P450, family 3, subfamily A, polypeptide 7 [ Homo sapiens ]
• Official Symbol: CYP3A7
• Synonyms: CYP3A7; cytochrome P450, family 3, subfamily A, polypeptide 7; cytochrome P450, subfamily IIIA, polypeptide 7; cytochrome P450 3A7; CP37; P450 HFLA; cytochrome P450-HFLA; microsomal monooxygenase; xenobiotic monooxygenase; aryl hydrocarbon hydroxylase; flavoprotein-linked monooxygenase; CYPIIIA7; P450-HFLA
• Gene ID: 1551
• mRNA Refseq: NM_000765
• Protein Refseq: NP_000756
• MIM: 605340
• UniProt ID: P24462