Recombinant Human CYP4F12 Protein, GST-tagged

• Cat.No.: CYP4F12-2283H
• Product Overview: Human CYP4F12 full-length ORF ( AAH35350, 1 a.a. - 524 a.a.) recombinant protein with GST-tag at N-terminal.

Specification

• Description: This gene encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. This protein likely localizes to the endoplasmic reticulum. When expressed in yeast the enzyme is capable of oxdizing arachidonic acid. It can also catalyze the epoxidation of 22:6n-3 and 22:5n-3 polyunsaturated long-chain fatty acids. This gene is part of a cluster of cytochrome P450 genes on chromosome 19. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Apr 2014]
• Source: Wheat Germ
• Species: Human
• Tag: GST
• Molecular Mass: 83.38 kDa
• AA Sequence: MSLLSLPWLGLRPVAMSPWLLLLLV VGSWLLARILAWTYAFYNNCRRLQC FPQPPKRNWFWGHLGLITPTEEGLK DSTQMSATYSQGFTVWLGPIIPLIV LCHPDTIRSITNASAAIAPKDNLFI RFLKPWLGEGILLSGGDKWSRHRRM LTPAFHFNILKSYITIFNKSANIML DKWQHLASEGSSCLDMFEHISLMTL DSLQKCIFSFDSHCQERPSEYIATI LELSALVEKRSQHILQHMDFLYYLS HDGRRFHRACRLVHDFTDAVIRERR RTLPTQGIDDFFKDKAKSKTLDFID VLLLSKDEDGKALSDEDIRAEADTF MFGGHDTTASGLSWVLYNLARHPEY QERCRQEVQELLKDRDPKEIEWDDL AQLPFLTMCVKESLRLHPPAPFISR CCTQDIVLPDGRVIPKGITCLIDII GVHHNPTVWPDPEVYDPFRFDPENS KGRSPLAFIPFSAGPRNCIGQAFAM AEMKVVLALMLLHFRFLPDHTEPRR KLELIMRAEGGLWLRVEPLNVSLQ
• Applications: Enzyme-linked Immunoabsorbent Assay
  Western Blot (Recombinant protein)
  Antibody Production
  Protein Array
• Notes: Best use within three months from the date of receipt of this protein.
• Storage: Store at -80 centigrade. Aliquot to avoid repeated freezing and thawing.
• Storage Buffer: 50 mM Tris-HCI, 10 mM reduced Glutathione, pH=8.0 in the elution buffer.

Gene Information

• Gene Name: CYP4F12 cytochrome P450, family 4, subfamily F, polypeptide 12 [ Homo sapiens ]
• Official Symbol: CYP4F12
• Synonyms: CYP4F12; cytochrome P450, family 4, subfamily F, polypeptide 12; cytochrome P450, subfamily IVF, polypeptide 12; cytochrome P450 4F12; CYPIVF12; F22329_1
• Gene ID: 66002
• mRNA Refseq: NM_023944
• Protein Refseq: NP_076433
• MIM: 611485
• UniProt ID: Q9HCS2