Recombinant Human CYP7A1 Protein, GST-tagged
Cat.No. : | CYP7A1-2291H |
Product Overview : | Human CYP7A1 partial ORF (NP_000771.2, 179 a.a. - 277 a.a.) recombinant protein with GST tag at N-terminal. |
- Specification
- Gene Information
- Related Products
Description : | This gene encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. This endoplasmic reticulum membrane protein catalyzes the first reaction in the cholesterol catabolic pathway in the liver, which converts cholesterol to bile acids. This reaction is the rate limiting step and the major site of regulation of bile acid synthesis, which is the primary mechanism for the removal of cholesterol from the body. Polymorphisms in the promoter of this gene are associated with defects in bile acid synthesis. [provided by RefSeq, Feb 2010] |
Source : | Wheat Germ |
Species : | Human |
Tag : | GST |
Molecular Mass : | 36.63 kDa |
AA Sequence : | MFEAGYLTIFGRDLTRRDTQKAHIL NNLDNFKQFDKVFPALVAGLPIHMF RTAHNAREKLAESLRHENLQKRESI SELISLRMFLNDTLSTFDDLEKAK |
Applications : | Enzyme-linked Immunoabsorbent Assay Western Blot (Recombinant protein) Antibody Production Protein Array |
Notes : | Best use within three months from the date of receipt of this protein. |
Storage : | Store at -80 centigrade. Aliquot to avoid repeated freezing and thawing. |
Storage Buffer : | 50 mM Tris-HCI, 10 mM reduced Glutathione, pH=8.0 in the elution buffer. |
Gene Name : | CYP7A1 cytochrome P450, family 7, subfamily A, polypeptide 1 [ Homo sapiens ] |
Official Symbol : | CYP7A1 |
Synonyms : | CYP7A1; cytochrome P450, family 7, subfamily A, polypeptide 1; CYP7, cytochrome P450, subfamily VIIA (cholesterol 7 alpha monooxygenase), polypeptide 1; cholesterol 7-alpha-monooxygenase; cholesterol 7 alpha monooxygenase; cytochrome P450 7A1; cholesterol 7-alpha-hydroxylase; cytochrome P450, subfamily VIIA polypeptide 1; CP7A; CYP7; CYPVII; MGC126826; MGC138389; |
Gene ID : | 1581 |
mRNA Refseq : | NM_000780 |
Protein Refseq : | NP_000771 |
MIM : | 118455 |
UniProt ID : | P22680 |
Products Types
◆ Recombinant Protein | ||
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Cyp7a1-2425M | Recombinant Mouse Cyp7a1 Protein, Myc/DDK-tagged | +Inquiry |
CYP7A1-2425H | Recombinant Human CYP7A1 Protein, Myc/DDK-tagged | +Inquiry |
CYP7A1-2163M | Recombinant Mouse CYP7A1 Protein, His (Fc)-Avi-tagged | +Inquiry |
CYP7A1-1416R | Recombinant Rat CYP7A1 Protein, His (Fc)-Avi-tagged | +Inquiry |
◆ Lysates | ||
CYP7A1-7099HCL | Recombinant Human CYP7A1 293 Cell Lysate | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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