| Description : |
This gene encodes a member of the PSCD (pleckstrin homology, Sec7 and coiled-coil domains) family. PSCD family members have identical structural organization that consists of an N-terminal coiled-coil motif, a central Sec7 domain, and a C-terminal pleckstrin homology (PH) domain. The coiled-coil motif is involved in homodimerization, the Sec7 domain contains guanine-nucleotide exchange protein (GEP) activity, and the PH domain interacts with phospholipids and is responsible for association of PSCDs with membranes. Members of this family appear to mediate the regulation of protein sorting and membrane trafficking. This encoded protein is involved in the control of Golgi structure and function, and it may have a physiological role in regulating ADP-ribosylation factor protein 6 (ARF) functions, in addition to acting on ARF1. |
| Source : |
HEK293 |
| Species : |
Human |
| Tag : |
Myc/DDK |
| Molecular Mass : |
46.3 kDa |
| AA Sequence : |
MDEDGGGEGGGVPEDLSLEEREELL DIRRRKKELIDDIERLKYEIAEVMT EIDNLTSVEESKTTQRNKQIAMGRK KFNMDPKKGIQFLIENDLLQSSPED VAQFLYKGEGLNKTVIGDYLGERDE FNIKVLQAFVELHEFADLNLVQALR QFLWSFRLPGEAQKIDRMMEAFASR YCLCNPGVFQSTDTCYVLSFAIIML NTSLHNHNVRDKPTAERFIAMNRGI NEGGDLPEELLRNLYESIKNEPFKI PEDDGNDLTHTFFNPDREGWLLKLG GRVKTWKRRWFILTDNCLYYFEYTT DKEPRGIIPLENLSIREVEDPRKPN CFELYNPSHKGQVIKACKTEADGRV VEGNHVVYRISAPSPEEKEEWMKSI KASISRDPFYDMLATRKRRIANKKT RTRPLEQKLISEEDLAANDILDYKD DDDKV |
| Purity : |
> 80% as determined by SDS-PAGE and Coomassie blue staining |
| Stability : |
Stable for 3 months from receipt of products under proper storage and handling conditions. |
| Storage : |
Store at -80 centigrade. Avoid repeated freeze-thaw cycles. |
| Concentration : |
50 μg/mL as determined by BCA |
| Storage Buffer : |
100 mM glycine, 25 mM Tris-HCl, pH 7.3. |
