Recombinant Human DACH2 Protein, GST-tagged

• Cat.No.: DACH2-2321H
• Product Overview: Human DACH2 full-length ORF (BAC03761.1, 1 a.a. - 571 a.a.) recombinant protein with GST-tag at N-terminal.

Specification

• Description: This gene is one of two genes which encode a protein similar to the Drosophila protein dachshund, a transcription factor involved in cell fate determination in the eye, limb and genital disc of the fly. The encoded protein contains two characteristic dachshund domains: an N-terminal domain responsible for DNA binding and a C-terminal domain responsible for protein-protein interactions. This gene is located on the X chromosome and is subject to inactivation by DNA methylation. The encoded protein may be involved in regulation of organogenesis and myogenesis, and may play a role in premature ovarian failure. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Nov 2008]
• Source: Wheat Germ
• Species: Human
• Tag: GST
• Molecular Mass: 88.3 kDa
• AA Sequence: MAVSASPVISATSSGAGVPGGLFRA EPLYSTPREPPRLTPNMINSFVVNN HSNSAGGGGRGNTNTNECRMVDMHG MKVASFLMDGQELICLPQVFDLFLK HLVGGLHTVYTKLKRLDISPVVCTV EQVRILRGLGAIQPGVNRCKLITRK DFETLFTDCTNASSRPGRPPKRSLG VLQENARLLTHAVPGLLSPGLITPT GITAAAMAEAMKLQKMKLMAMNTLQ GNGSQNGTESEPDDLNSNTGGSESS WDKDKMQSPFAAPGPQHGIAHAALA GQPGIGGAPTLNPLQQNHLLTNRLD LPFMMMPHPLLPVSLPPASVAMAMN QMNHLNTIANMAAAAQIHSPLSRAG TSVIKERIPESPSPAPSLEENHRPG SQTSSHTSSSVSSSPSQMDHHLERM EEVPVQIPIMKSPLDKIQLTPGQAL PAGFPGPFIFADSLSSVETLLTNIQ GLLKVALDNARIQEKQIQQEKKELR LELYREREIRENLERQLAVELQSRT TMQKRLKKEKKTKRKLQEALEFESK RREQVEQALKQATTSDSGLRMLKDT GIPDIEIENNGTPHDSAAMQA
• Applications: Enzyme-linked Immunoabsorbent Assay
  Western Blot (Recombinant protein)
  Antibody Production
  Protein Array
• Notes: Best use within three months from the date of receipt of this protein.
• Storage: Store at -80 centigrade. Aliquot to avoid repeated freezing and thawing.
• Storage Buffer: 50 mM Tris-HCI, 10 mM reduced Glutathione, pH=8.0 in the elution buffer.

Gene Information

• Gene Name: DACH2 dachshund homolog 2 (Drosophila) [ Homo sapiens ]
• Official Symbol: DACH2
• Synonyms: DACH2; dachshund homolog 2 (Drosophila); dachshund homolog 2; FLJ31391; MGC138545
• Gene ID: 117154
• mRNA Refseq: NM_001139514
• Protein Refseq: NP_001132986
• MIM: 300608
• UniProt ID: Q96NX9