Recombinant Human DARS Protein, GST-tagged

• Cat.No.: DARS-2348H
• Product Overview: Human DARS full-length ORF ( AAH00629, 1 a.a. - 501 a.a.) recombinant protein with GST-tag at N-terminal.

Specification

• Description: This gene encodes a member of a multienzyme complex that functions in mediating the attachment of amino acids to their cognate tRNAs. The encoded protein ligates L-aspartate to tRNA(Asp). Mutations in this gene have been found in patients showing hypomyelination with brainstem and spinal cord involvement and leg spasticity. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jun 2014]
• Source: Wheat Germ
• Species: Human
• Tag: GST
• Molecular Mass: 80.85 kDa
• AA Sequence: MPSASASRKSQEKPREIMDAAEDYA KERYGISSMIQSQEKPDRVLVRVRD LTIQKADEVVWVRARVHTSRAKGKQ CFLVLRQQQFNVQALVAVGDHASKQ MVKFAANINKESIVDVEGVVRKVNQ KIGSCTQQDVELHVQKIYVISLAEP RLPLQLDDAVRPEAEGEEEGRATVN QDTRLDNRVIDLRTSTSQAVFRLQS GICHLFRETLINKGFVEIQTPKIIS AASEGGANVFTVSYFKNNAYLAQSP QLYKQMCICADFEKVFSIGPVFRAE DSNTHRHLTEFVGLDIEMAFNYHYH EVMEEIADTMVQIFKGLQERFQTEI QTVNKQFPCEPFKFLEPTLRLEYCE ALAMLREAGVEMGDEDDLSTPNEKL LGHLVKEKYDTDFYILDKYPLAVRP FYTMPDPRNPKQSNSYDMFMRGEEI LSGAQRIHDPQLLTERALHHGIDLE KIKAYIDSFRFGAPPHAGGGIGLER VTMLFLGLHNVRQTSMFPRDPKRLT P
• Applications: Enzyme-linked Immunoabsorbent Assay
  Western Blot (Recombinant protein)
  Antibody Production
  Protein Array
• Notes: Best use within three months from the date of receipt of this protein.
• Storage: Store at -80 centigrade. Aliquot to avoid repeated freezing and thawing.
• Storage Buffer: 50 mM Tris-HCI, 10 mM reduced Glutathione, pH=8.0 in the elution buffer.

Gene Information

• Gene Name: DARS aspartyl-tRNA synthetase [ Homo sapiens ]
• Official Symbol: DARS
• Synonyms: DARS; aspartyl-tRNA synthetase; aspartate--tRNA ligase, cytoplasmic; aspartate tRNA ligase 1; cytoplasmic; aspRS; aspartate tRNA ligase 1, cytoplasmic; aspartyl-tRNA synthetase, cytoplasmic; cell proliferation-inducing protein 40; cell proliferation-inducing gene 40 protein; MGC111579; DKFZp781B11202
• Gene ID: 1615
• mRNA Refseq: NM_001349
• Protein Refseq: NP_001340
• MIM: 603084
• UniProt ID: P14868