Recombinant Human DCLRE1C Protein, GST-tagged

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Recombinant Human DCLRE1C Protein, GST-tagged

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Cat.No. : DCLRE1C-2396H
Product Overview : Human DCLRE1C full-length ORF ( AAH22254, 1 a.a. - 434 a.a.) recombinant protein with GST-tag at N-terminal.
Description : This gene encodes a nuclear protein that is involved in V(D)J recombination and DNA repair. The encoded protein has single-strand-specific 5'-3' exonuclease activity; it also exhibits endonuclease activity on 5' and 3' overhangs and hairpins. The protein also functions in the regulation of the cell cycle in response to DNA damage. Mutations in this gene can cause Athabascan-type severe combined immunodeficiency (SCIDA) and Omenn syndrome. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jan 2014]
Source : Wheat Germ
Species : Human
Tag : GST
Molecular Mass : 73.48 kDa
AA Sequence : MSSFEGQMAE YPTISIDRFD RENLRARAYF LSHCHKDHMK GLRAPTLKRR LECSLKVYLY CSPVTKELLL TSPKYRFWKK RIISIEIETP TQISLVDEAS GEKEEIVVTL LPAGHCPGSV MFLFQGNNGT VLYTGDFRLA QGEAARMELL HSGGRVKDIQ SVYLDTTFCD PRFYQIPSRE ECLSGVLELV RSWITRSPYH VVWLNCKAAY GYEYLFTNLS EELGVQVHVN KLDMFRNMPE ILRHLTTDRN TQIHACRHPK AEEYFQWSKL PCGITSRNRI PLHIISIKPS TMWFGERSRK TNVIVRTGES SYRACFSFHS SYSEIKDFLS YLCPVNAYPN VIPVGTTMDK VVEILKPLCR SSQSTEPKYK PLGKLKRART VHRDSGSHSV TQARMRWCHH DSLYPLTPGI KRSSCLSLLT SWITGAYRHA QLMI
Applications : Enzyme-linked Immunoabsorbent Assay
Western Blot (Recombinant protein)
Antibody Production
Protein Array
Notes : Best use within three months from the date of receipt of this protein.
Storage : Store at -80 centigrade. Aliquot to avoid repeated freezing and thawing.
Storage Buffer : 50 mM Tris-HCI, 10 mM reduced Glutathione, pH=8.0 in the elution buffer.
Quality Control Testing: :

12.5% SDS-PAGE Stained with Coomassie Blue.

Gene Name : DCLRE1C DNA cross-link repair 1C [ Homo sapiens ]
Official Symbol : DCLRE1C
Synonyms : DCLRE1C; DNA cross-link repair 1C; DNA cross link repair 1C (PSO2 homolog, S. cerevisiae) , SCIDA, severe combined immunodeficiency, type a (Athabascan); protein artemis; A SCID; ARTEMIS; FLJ11360; PSO2 homolog (S. cerevisiae); SNM1C; PSO2 homolog; SNM1 homolog C; SNM1-like protein; DNA cross-link repair 1C protein; severe combined immunodeficiency, type a (Athabascan); DNA cross-link repair 1C (PSO2 homolog, S. cerevisiae); SCIDA; A-SCID; hSNM1C; RS-SCID; DCLREC1C; FLJ36438;
Gene ID : 64421
mRNA Refseq : NM_001033855
Protein Refseq : NP_001029027
MIM : 605988
UniProt ID : Q96SD1

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